Search for dissertations about: "genome-wide linkage analysis"
Showing result 1 - 5 of 62 swedish dissertations containing the words genome-wide linkage analysis.
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1. Genetic linkage and association studies in celiac disease: discoveries from whole genome analysis
Abstract : Celiac Disease (CD) or Gluten Sensitive Enteropathy (GSE) is a life-long disorder. It is characterized by inflammation in the small intestine of genetically predisposed individuals caused by inappropriate immune response to gluten, a protein enriched in some of our common grains (wheat, rye and barley). READ MORE
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2. Mapping genetic diseases in northern Sweden
Abstract : The population of northern Sweden has previously been shown to be well suited for the mapping of monogenic diseases. In this thesis we have tested the hypothesis that this population could also be used for efficient identification of risk genes for common diseases. READ MORE
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3. Two Optimization Problems in Genetics : Multi-dimensional QTL Analysis and Haplotype Inference
Abstract : The existence of new technologies, implemented in efficient platforms and workflows has made massive genotyping available to all fields of biology and medicine. Genetic analyses are no longer dominated by experimental work in laboratories, but rather the interpretation of the resulting data. READ MORE
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4. Genetic studies of stroke in Northern Sweden
Abstract : Stroke is a common disorder of later life with a complex etiology, including both environmental and genetic risk factors. The inherited predisposition is challenging to study due to the complexity of the stroke phenotype. READ MORE
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5. Genetic epidemiology of prostate cancer
Abstract : Prostate cancer is a major health burden throughout the world, yet the etiology of prostate cancer is poorly understood. Evidence has accumulated supporting the existence of a hereditary form of this disease. READ MORE