Search for dissertations about: "genome-wide scan"

Showing result 21 - 25 of 31 swedish dissertations containing the words genome-wide scan.

  1. 21. Genetic studies of diabetes in northern Sweden

    University dissertation from Umeå : Medicinsk biovetenskap

    Author : Sofia Mayans; Umeå universitet.; [2008]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Diabetes; families; genetic; association; SNP; linkage; TCF7L2; CTLA-4; Calpain-10; MEDICINE Dermatology and venerology; clinical genetics; internal medicine Clinical genetics Medical genetics; MEDICIN Dermatologi och venerologi; klinisk genetik; invärtesmedicin Klinisk genetik Medicinsk genetik;

    Abstract : Diabetes mellitus represents a group of metabolic disorders caused by both environmental and genetic factors. The two most common forms of diabetes are type 2 diabetes (T2D) and type 1 diabetes (T1D). T2D is associated with obesity and the disease is caused by insulin resistance and pancreatic b-cell dysfunction. READ MORE

  2. 22. FOXC2 and CAPN10 as candidate genes for obesity, insulin resistance and type 2 diabetes

    University dissertation from Endocrinology

    Author : Emma A Nilsson; [2005]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biomedicinska vetenskaper; Biomedical sciences; Type 2 diabetes; Genetics; Obesity;

    Abstract : The worldwide prevalence of obesity and type 2 diabetes is increasing rapidly. Both disorders depend on genetic and environmental factors. The studies included in this thesis investigated the possible association of the FOXC2 and CAPN10 genes with obesity, insulin resistance, type 2 diabetes, and related phenotypes. READ MORE

  3. 23. Genetic studies of susceptibility to diabetes mellitus with emphasis on type 1 diabetes

    University dissertation from Stockholm : Karolinska Institutet, Department of Molecular Medicine

    Author : Pernilla Holm; Karolinska Institutet.; Karolinska Institutet.; [2003]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : Diabetes mellitus is a common multifactorial disease that needs lifelong treatment of insulin and/or oral treatment to prevent hyperglycaemia. Despite treatment, patients with diabetes, still suffer from severe complications later in life. READ MORE

  4. 24. Identification of candidate genes involved in Mercury Toxicokinetics and Mercury Induced Autoimmunity

    University dissertation from Linköping : Linköping University Electronic Press

    Author : Hammoudi Alkaissi; Linköpings universitet.; Linköpings universitet.; [2018]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES;

    Abstract : BACKGROUND: Autoimmune diseases require the involvement and activation of immune cells and occur when the body builds up an immune response against its own tissues. This process takes place due to the inability to distinguish self-antigen from foreign antigen. Systemic autoimmunity represents an important cause of morbidity and mortality in humans. READ MORE

  5. 25. Molecular Genetic Studies of ALSG, Kostmann Syndrome and a Novel Chromosome 10 Inversion

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Miriam Entesarian; Uppsala universitet.; [2009]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICINE Dermatology and venerology; clinical genetics; internal medicine Clinical genetics; MEDICIN Dermatologi och venerologi; klinisk genetik; invärtesmedicin Klinisk genetik; Clinical Genetics; klinisk genetik;

    Abstract : In summary, this thesis presents the localisation and identification of genetic variants of which some are disease associated and some considered to be neutral. Knowledge of the basic mechanisms behind human disorders is important both from a biological and medical point of view. READ MORE