Search for dissertations about: "genome"

Showing result 11 - 15 of 1778 swedish dissertations containing the word genome.

  2. 11. Catching the Spore killers : Genomic conflict and genome evolution in Neurospora

    Author : Jesper Svedberg; Hanna Johannesson; Mark A. Kirkpatrick; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Genomics; genomic conflict; genome evolution; meiotic drive; spore killer; suppression of recombination; inversions; fungi; Neurospora; Biologi; Biology;

    Abstract : A genome is shaped by many different forces. Recombination can for instance both create and maintain genetic diversity, but the need to locally reduce recombination rates will also leave specific signatures. READ MORE

  4. 12. Genetic Analysis of Quantitative Traits Using Domestic Animals : A Candidate Gene and Genome Scanning Approach

    Author : Hee-Bok Park; Leif Andersson; Stefan Marklund; Robert Fredricksson; Holger Luthman; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Genetics; Domestication; horse; pig; chicken; quantitative traits; candidate gene; genome scan; PRKAG3; MC4R; selection experiment; growth; correlated response; metabolic disorders; Quantitative Trait Loci; linkage; single nucleotide polymorphisms; Genetik; Clinical genetics; Klinisk genetik;

    Abstract : Domestication has led to genetic changes that affect quantitative traits in farm animals. Both candidate gene analysis using association tests and genome scans based on linkage analysis have been performed to understand the molecular basis underlying quantitative genetic variation in horses, pigs and chickens. READ MORE

  5. 13. Technologies for Single Cell Genome Analysis

    Author : Erik Borgström; Afshin Ahmadian; Sten Linnarsson; KTH; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; DNA; sequencing; single molecule; single cell; whole genome amplification; exome sequencing; emulsions; barcoding; phasin; Biotechnology; Bioteknologi;

    Abstract : During the last decade high throughput DNA sequencing of single cells has evolved from an idea to one of the most high profile fields of research. Much of this development has been possible due to the dramatic reduction in costs for massively parallel sequencing. READ MORE

  6. 14. Lifestyle and Genome Evolution in Vector-Borne Bacteria : A Comparison of Three Bartonella Species

    Author : Anna Carolin Frank; Siv Andersson; Stewart Cole; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Biology; Bartonella; evolution; host-restriction; vector-borne; horizontal gene transfer; genome reduction; alpha-proteobacteria; Type-IV secretion; Biologi; Biology; Biologi;

    Abstract : Bacterial genomes provide records of the molecular processes associated with emergence and evolution of different bacterial lifestyles. This thesis is based on whole-genome comparisons within the genus Bartonella, an excellent model system for studies of host- and vector-specificity and infection outcome in animal-associated bacteria. READ MORE

  7. 15. Rates and patterns of genome evolution in Lepidoptera

    Author : Karin Näsvall; Niclas Backström; Simon Martin; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Chromosomal rearrangements; karyotype evolution; recombination rate; Lepidoptera; genome structure; molecular evolution; Biology with specialization in Evolutionary Genetics; Biologi med inriktning mot evolutionär genetik;

    Abstract : The evolutionary consequences of genome restructuring and chromosomal rearrangements can be significant, but the underlying mechanisms are poorly understood. This thesis explores the relationships between genome restructuring, recombination, and maintenance of genetic diversity in different butterfly species. READ MORE