Search for dissertations about: "genomics"

Showing result 1 - 5 of 249 swedish dissertations containing the word genomics.

  1. 1. Speciation genomics A perspective from vertebrate systems

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Nagarjun Vijay; Jochen. B.W Wolf; C. Alex Buerkle; [2016]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; evolution; speciation; genomics; vertebrate; adaptation; selection; linked selection; crow; killer whale; hybrid zone; transcriptomics; population genetics; behaviour; colouration; Biology with specialization in Evolutionary Genetics; Biologi med inriktning mot evolutionär genetik;

    Abstract : Species are vital entities in biology. Species are generally considered to be discrete entities, consisting of a group of (usually interbreeding) individuals that are similar in phenotype and genetic composition, yet differ in significant ways from other species. READ MORE

  2. 2. Evolutionary genomics in Corvids – From single nucleotides to structural variants

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Matthias H. Weissensteiner; Jochen B.W. Wolf; Manfred Grabherr; Kateryna M. Makova; [2019]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; evolutionary genetics; genomics; population genetics; selection; recombination; chromosomal features; colouration; insertion; deletion; inversion; crow; tandem repeat; transposable element; gene expression;

    Abstract : Heritable genetic variation is the raw material of evolution and can occur in many different forms, from altering single nucleotides to rearranging stretches of millions at once. DNA mutations that result in phenotypic differences are the basis upon which natural selection can act, leading to a shift of the frequency of those mutations. READ MORE

  3. 3. Complex disease genetics Utilising targeted sequencing and homogeneous ancestry

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Argyri Mathioudaki; Kerstin Lindblad-Toh; Panagiotis Deloukas; [2019]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; ankylosing spondylitis; breast cancer; targeted sequencing; Sweden; genetics; population stratification.; Molekylär genetik; Molecular Genetics;

    Abstract : The complex disease investigations presented in this thesis aimed to provide new information regarding underlying genetics by using targeted sequencing and ethnically homogeneous cohorts. This work moved past current methodologies and addressed data stratification issues, that might have been hindering new findings. READ MORE

  4. 4. Adaptive divergence in fission yeast From experimental evolution to evolutionary genomics

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Sergio Ivan Tusso Gomez; Jochen B.W. Wolf; Simone Immler; Roger K. Butlin; [2019]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; adaptation; divergence; selection; experimental evolution; genomics; genome evolution; population genetics; fission yeast; phenotypic variation; Biology with specialization in Evolutionary Genetics; Biologi med inriktning mot evolutionär genetik;

    Abstract : How adaptation and population differentiation occur is fundamental to understand the origin of biodiversity. Work in speciation alongside the increased ease of generating genomic data have allowed the exploration of genomic changes relevant to adaptation. READ MORE

  5. 5. Comparative Genomics in Diplomonads Lifestyle Variations Revealed at Genetic Level

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Feifei Xu; Jan O. Andersson; Staffan G. Svärd; Matt Berriman; [2015]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; comparative genomics; Giardia intestinalis; Spironucleus salmonicida; Trepomonas; diplomonad; intestinal parasite; free-living; sexual recombination; hydrogenosome; horizontal gene transfer; Biologi med inriktning mot molekylär evolution; Biology with specialization in Molecular Evolution;

    Abstract : As sequencing technologies advance genome studies are becoming a basic tool for studying an organism, and with more genomes available comparative genomics is maturing into a powerful tool for biological research. This thesis demonstrates the strength of a comparative genomics approach on a group of understudied eukaryotes, the diplomonads. READ MORE