Search for dissertations about: "genotoxic"

Showing result 1 - 5 of 87 swedish dissertations containing the word genotoxic.

  2. 1. Cyclotides : Tuning Parameters Toward Their Use in Drug Design

    Author : Mariamawit Yonathan Yeshak; Ulf Göransson; Lars Bohlin; Kaleab Asres; Robert Kiss; Uppsala universitet; []
    Keywords : cyclotide; Viola abyssinica; Viola odorata; Extraction; Violaceae; vaby; cytotoxic; genotoxic; cell penetrating; microautoradiography; LC-MS; comet assay; cycloviolacin O2; Farmakognosi; Pharmacognosy;

    Abstract : Cyclotides are plant proteins with a unique topology, defined as the cyclic cystine knot motif. The motif endows cyclotides with exceptional chemical and biological stability. They also exhibit a wide range of biological activities including insecticidal, cytotoxic, anti-HIV and antimicrobial effects. READ MORE

  4. 2. Immunomodulatory and genotoxic effects of mycotoxins

    Author : Ruby Cooray; Uppsala universitet; []
    Keywords : NATURAL SCIENCES; NATURVETENSKAP;

    Abstract : .... READ MORE

  5. 3. Genotoxic hazards in the rubber industry : application of short-term tests in work environment analyses

    Author : Agneta Rannug; Stockholms universitet; []
    Keywords : ;

    Abstract : Excess mortality from a number of different types of cancer has been associated with work in the rubber industry. The aim of the present study - using short-term tests for mutagenicity - was to identify potentially hazardous additives and process fumes to which workers are exposed. READ MORE

  6. 4. Response mechanisms of normal hematopoietic cells and leukemic cells to genotoxic agents and novel therapeutic strategies

    Author : Andreas Hedblom; Malmö Experimentell cancerforskning; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Hematopoietic stem cells; genotoxic damage; cell cycle; leukemia; heme oxygenase; differentiation;

    Abstract : Hematopoiesis is initiated by a rare population of hematopoietic stem cells (HSC) in the bone marrow (BM). HSCs give rise to red blood cells and white blood cells of myeloid and lymphoid lineages. READ MORE

  7. 5. Methods for assessing the genotoxic potency of polycyclic aromatic hydrocarbons and complex mixtures

    Author : Michael Sjögren; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Carcinogener; PAH; Genotoxicitet; Metoder; Blandningar; Polycykliska aromatiska föreningar;

    Abstract : .... READ MORE