Search for dissertations about: "genotyping methods"
Showing result 1 - 5 of 99 swedish dissertations containing the words genotyping methods.
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1. Methods for Analyzing Genomes
Abstract : The human genome reference sequence has given us a two‐dimensional blueprint of our inherited code of life, but we need to employ modern‐day technology to expand our knowledge into a third dimension. Inter‐individual and intra‐individual variation has been shown to be larger than anticipated, and the mode of genetic regulation more complex. READ MORE
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2. Multiplex HLA-DR-DQ genotyping : for genetic epidemiology and clinical risk assessment
Abstract : The human leukocyte antigens (HLA) are highly polymorphic cell surface proteins encoded in the major histocompatibility complex (MHC) region on chromosome 6. The HLA system has been well known as transplantation antigens but the primary biological role of the HLA molecules is regulation of immune response by presenting peptide fragments to T-lymphocytes. READ MORE
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3. Chlamydia trachomatis: Development of molecular typing methods and applications in epidemiology
Abstract : A general aim was to combine molecular typing methods with clinical background information to increase epidemiological knowledge about Chlamydia trachomatis infections.An outbreak of Lymfogranuloma venereum (LGV), caused by a more invasive variant of C. trachomatis, was reported from the Netherlands in 2003 among men who have sex with men (MSM). READ MORE
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4. Detection of Chlamydia trachomatis and Mycoplasma genitalium by genetic and serological methods
Abstract : Chlamydia trachomatis infections are associated with a spectrum of clinical diseases including urethritis, prostatitis and epididymitis among men and cervicitis and pelvic inflammatory disease (PID), with an increased risk of infertility and ectopic pregnancy (EP), among women. In the search for other pathogens causing urethritis, Mycoplasma genitalium was isolated from urethral specimens from two men with acute urethritis (1980). READ MORE
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5. Detection and Characterisation of Salmonella in Animal Feed Samples by PCR-Based Methods
Abstract : Animal feed is a recognised source of Salmonella enterica for farm livestock and may also indirectly cause infection in people consuming foods of animal origin. It is therefore important to have rapid, reproducible and specific methods for the detection of Salmonella in feed, and for the characterisation of strains for further epidemiological investigations or to trace the source of contamination in a production facility. READ MORE