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Showing result 1 - 5 of 94 swedish dissertations matching the above criteria.

2. 1. Gingival recession development in orthodontic patients : studies on gingival phenotype diagnostics, local and systemic biomarkers, and the impact of orthodontic treatment on gingival recession development

   Author : Dimitrios Kloukos; Andreas Stavropoulos; Christos Katsaros; Timo Peltomäki; Malmö universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

   Abstract : Gingival recession refers to the apical displacement of the gingival margin from the cemento-enamel junction, resulting in exposure of the root of the tooth. Recessions can be localized, involving a single surface and tooth or may involve more tooth surfaces and/or teeth. READ MORE

4. 2. Prostaglandin E synthases in periodontitis-affected gingival tissue and in gingival fibroblasts

   Author : Tove Båge; Karolinska Institutet; Karolinska Institutet; []
   Keywords : c-Jun N-terminal kinase;

   Abstract : Periodontitis is a chronic inflammatory disease resulting in the destruction of the tissue and alveolar bone supporting the teeth and leading ultimately to tooth loss. Prostaglandin E2 (PGE2) is an important inflammatory mediator in the pathogenesis of periodontitis. READ MORE

5. 3. Regulation of prostaglandin E2 synthesis in human gingival fibroblasts

   Author : Tülay Yucel-Lindberg; Karolinska Institutet; Karolinska Institutet; []
   Keywords : prostaglandin E2; cyclooxygenase; phospholipase A2 interleukin-1; tumor necrosis factor [alpha]; epidermal growth factor; protein kinase C; tyrosine kinases; human gingival fibroblasts;

   Abstract : Prostaglandins, especially, prostaglandin E2 (PGE2) play an important role in inflammatory diseases such as rheumatoid arthritis and periodontitis. The aim of the present thesis was to study the production and the regulation of PGE2 with special reference to the key enzymes phospholipase A2 (PLA2) and cyclooxygenase (COX) at the rnRNA level in human gingival fibroblasts. READ MORE

6. 4. Cyclosporin A-induced gingival overgrowth in renal transplant patients : a clinical, histological and experimental study

   Author : Biniyam Wondimu; Karolinska Institutet; Karolinska Institutet; []
   Keywords : cyclosporin A gingival overgrowth gingival fibroblasts nephrotoxicity renal transplant saliva;

   Abstract : Cyclosporine A (CsA) is widely used as an effective immunosuppressive agent to prevent rejection of organ transplants, as well as in the treatment of patients with various autoimmune diseases. The clinical use of CsA, however, is associated with adverse side effects, including nephrotoxicity, hepatotoxicity, hypertension, and neurotoxicity as well as gingival overgrowth. READ MORE

7. 5. Osteotropic cytokines : expression in human gingival fibroblasts and effects on bone

   Author : Py Palmqvist; Andersson Göran; Umeå universitet; []
   Keywords : osteoblasts; osteoclasts; fibroblasts; cytokines; IL-6; LIF; OSM; IL-4; IL-3; bone resorption; odontologi; Odontology;

   Abstract : Bone metabolism is regulated by endocrine and paracrine signalling molecules influencing bone cells in the continuously remodelling bone tissue. These molecules include a variety of osteotropic stimulatory and inhibitory cytokines. READ MORE