Search for dissertations about: "glargine"

Showing result 1 - 5 of 7 swedish dissertations containing the word glargine.

  1. 1. Glycaemic control: evaluation of HbA1c as a risk factor and the effect of modern insulins in clinical practice

    Author : Marcus Lind; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Keywords : HbA1c; glargine; lispro; time; retinopathy; clinical practice; electronical tracking; record system;

    Abstract : One of the ultimate goals of diabetes care is to minimise diabetic complications. When evaluating insulins it is important to understand what extent of improvements in glycaemic control is clinically relevant in preventing diabetic complications. READ MORE

  2. 2. Assessment and Treatment of Impaired Insulin- Secretion and Action in Type 2 Diabetes

    Author : Mozhgan Dorkhan; diabetes och endokrinologi Genomik; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Type 2 diabetes; insulin secretion; glucagon test; insulin resistance; insulin glargine; insulin tolerance test; thiazolidinediones; natriuretic peptides; adiponectin; thyroid associated ophthalmopathy; proinsulin;

    Abstract : Type 2 diabetes (T2D) is a disease characterised by varying degrees of defect in insulin secretion and insulin sensitivity and associated with increased morbidity and mortality. Optimal glycaemic control reduces the progression of diabetic complications. READ MORE

  3. 3. Long-acting insulin analogs in type 1 diabetes : effects on metabolic control, endogenous insulin production and the GH-IGF-axis

    Author : Jenny Salemyr; Karolinska Institutet; Karolinska Institutet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP;

    Abstract : The treatment goal in type 1 diabetes is to achieve near-normal glycemia. Despite of the advancements of subcutaneous insulin therapy and glucose monitoring, metabolic control is not fully normalized and secondary endocrine disturbances in the growth-hormone (GH) - Insulin-like Growth Factor (IGF)-axis are important for the deterioration of metabolic control, particularly in children at puberty. READ MORE

  4. 4. Expression and function of IGF-I and insulin receptors in human micro- and macrovascular cells

    Author : Simona I. Chisalita; Hans J. Arnqvist; Torbjorn Lindström; Per-Anders Jansson; Linköpings universitet; []
    Keywords : MEDICINE; MEDICIN;

    Abstract : Insulin-like growth factor and insulin are phylogenetically closely related polypeptides and have large structural and biological similarities. Low circulating insulin-like growth factor-I (IGF-I), diabetes as well as insulin resistance have been implicated in the pathogenesis of cardiovascular disease, but the mechanisms involved are still not clear. READ MORE

  5. 5. Insulin-like growth factor -I deficiency, insulin sensitivity, and glucose metabolism

    Author : Klas Ekström; Karolinska Institutet; Karolinska Institutet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP;

    Abstract : In children and adolescents, growth hormone (GH) and insulin-like growth factor-I (IGF-I) act in concert to stimulate linear growth; however, the effects on glucose metabolism are in opposition. GH increases insulin resistance by lipolysis. READ MORE