Search for dissertations about: "glial cell"

Showing result 21 - 25 of 270 swedish dissertations containing the words glial cell.

  2. 21. Sensory neuronal protection & improving regeneration after peripheral nerve injury

    Author : Andrew McKay Hart; Mikael Wiberg; Angus McGrouther; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neurosciences; cell death; TUNEL; optical disection; dorsal root ganglion; peripheral nerve; nerve conduit; Schwann cell; glial growth factor; leukaemia inhibitory factor; acetyl-L-carnitine; N-acetyl-cysteine; Neurovetenskap; Neurology; Neurologi; neurokirurgi; Neurosurgery;

    Abstract : Peripheral nerve trauma is a common cause of considerable functional morbidity, and healthcare expenditure. Particularly in the ~15% of injuries unsuitable for primary repair, standard clinical management results in inadequate sensory restitution in the majority of cases, despite the rigorous application of complex microsurgical techniques. READ MORE

  4. 22. Stem Cell Transplantation in Dorsal Root Injury

    Author : Carl Trolle; Elena Kozlova; Niklas Marklund; Karin Nordström; Michael Andäng; Mårten Risling; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Sensory Neuron; Regeneration; Spinal Root; Stem Cell; Neuroscience; Neurovetenskap;

    Abstract : After traumatic injuries to the brachial plexus there is a risk that one or more of the spinal roots are torn from the spinal cord, known as avulsion injury. This often leads to paralysis and chronic pain, notoriously difficult to treat with current pharmacotherapy. READ MORE

  5. 23. In vivo properties of neural stem cells after transplantation into the rat brain-Studies of phenotypic differentiation and functional integration using cell-specific labelling and electrophysiological techniques

    Author : Ulrica Englund Johansson; Peter Eriksson; Lund Oftalmologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cell line; Neurology; neuropsychology; neurophysiology; Neurologi; neuropsykologi; neurofysiologi; functional integration; electrophysiology; retrograde tracing; immortalized; GFP; migration; axonal projections; glia; neuron; transplantation; stem cell. progenitor cell; CNS; Biomedical Sciences;

    Abstract : In the present thesis, we have examined the in vivo properties of in vitro expanded human and rat neural stem-and progenitor cells after transplantation into the neonatal and adult rat brain. The survival and differentiation of the grafted cells were assessed using species-specific antisera, and pre-labelling with the reporter gene green fluorescent protein (GFP). READ MORE

  6. 24. Time-Lapse Microscopy Imaging and Image Analysis for Cell Migration Studies

    Author : Johan Degerman; Chalmers tekniska högskola; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; cell image segmentation; computational imaging; cell migration modelling; Time-lapse microscopy;

    Abstract : This thesis considers a complete automatic system for in-vitro cell imaging and migration image analysis. The development of such can be divided into three main problems:The first considered problem concerns how to build a robust time-lapse sequence acquisition system, for imaging adult hippocampal cells in bright-field microscopy. READ MORE

  7. 25. Stem cell transplantation and regeneration after dorsal root avulsion

    Author : Carl Trolle; Elena Kozlova; Adam Reid; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Regeneration; dorsal root; sensory nerve; nerve injury; cell transplantation; Medical Science; Medicinsk vetenskap;

    Abstract : Spinal root avulsion leads to paralysis and loss of sensory function. Surgical methods can improve motor function and ameliorate pain but sensory recovery in adults is poor. Previous studies have shown that cell transplantation or treatment with trophic factors can improve functional outcome in rodents after dorsal root transection or crush. READ MORE