Search for dissertations about: "glial progenitors"

Showing result 1 - 5 of 32 swedish dissertations containing the words glial progenitors.

  2. 1. Directing stem cells and progenitors towards neuronal differentiation - implications for experimental therapies for Parkinson's disease

    Author : Anke Brederlau; Göteborgs universitet; []
    Keywords : stem cells; Parkinson s disease; progenitors; BMP; ASK1; dopamine;

    Abstract : The insight that stem- and progenitor-cells contribute to replacement of nerve cells in the adult central nervous system is the basis of modern therapies for structural brain repair. Their goal is to protect, support and stimulate endogenous stem cells in areas affected by disease and to replace lost cells by transplanting in vitro generated, tailored nerve cells. READ MORE

  4. 2. Directing and Dissecting the Fate of Dopaminergic Neurons - Multiple Avenues towards Cell Replacement Therapy in Parkinson's Disease

    Author : Sara Nolbrant; Utvecklings- och regenerativ neurobiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Dopaminergic neurons; Cell replacement therapy; Parkinson s disease; Human pluripotent stem cells; Cell differentiation; Direct neuronal reprogramming; glial progenitors; midbrain development;

    Abstract : .... READ MORE

  5. 3. Neural progenitors for sensory and motor repair

    Author : Jan Hoeber; Elena Kozlova; Linda Greensmith; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Regenerative Neurobiology; Stem cells; Sensory regeneration; Spinal cord injury; Amyotrophic Lateral Sclerosis; Neurodegeneration; Oxidative Stress; Medical Science; Medicinsk vetenskap;

    Abstract : Injury and neurodegenerative conditions of the spinal cord can lead to paralysis and loss of sensation. Cell therapeutic approaches can restore sensory innervation of the spinal cord following injury and protect spinal cord cells from degeneration. READ MORE

  6. 4. Peripheral nerve glia as multipotent progenitors in craniofacial development

    Author : Maryam Khatibi Shahidi; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Craniofacial development is complex. Numerous populations of progenitor cells coordinate activities to produce an array of highly integrated tissues inside the developing head. However, it is not clear how some key multipotent progenitors continue to exist in late developing head compartments. READ MORE

  7. 5. Generation of functional neural progenitors for spinal cord transplantation

    Author : Jan Hoeber; Elena Kozlova; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Regenerative Neurobiology; Stem cells; Sensory regeneration; Spinal cord injury; Neuroscience; Neurovetenskap;

    Abstract : Dorsal root avulsion injuries result in permanent impairment of sensory functions due to the disconnection of the peripheral nervous system from the spinal cord. Strategies aiming for the functional reconnection of sensory neurons with their targets in the spinal cord dorsal horn need to overcome the axonal growth non-permissive glial scar and provide a growth promoting environment. READ MORE