Search for dissertations about: "glial-cell-line-derived-neurotrophic factor"

Showing result 11 - 15 of 41 swedish dissertations containing the words glial-cell-line-derived-neurotrophic factor.

  1. 11. Effects of Dopamine Signaling on Recovery and Inflammation after Ischemic Stroke

    Author : Enida Kuric; Neurokirurgi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : Ischemic stroke, resulting from occlusion of a brain artery is the most common type of stroke with a prevalence of 15 million people and the leading cause of long-term disability worldwide. Importantly, partial spontaneous recovery of lost neurological functions occurs mainly during the first months after stroke onset, albeit to a limited extent. READ MORE

  2. 12. Neurotrophic factors and neuronal plasticity

    Author : Sten Linnarsson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The neurotrophic factors were originally discovered because of their ability to rescue neurons during a period of naturally occurring programmed cell death. This gave rise to the neurotrophic factor hypothesis which states that specific target-derived factors protect and support subpopulations of innervating neurons, thereby regulating the pattern and quantity of innervation properly for each target tissue. READ MORE

  3. 13. Neurotrophic factors and their receptors in the developing avian retina and its tectal target

    Author : Miriam Karlsson; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neurosciences; Neurovetenskap; Neurology; Neurologi; Developmental Neurosciences; medicinsk utvecklings- och neurobiologi;

    Abstract : Neurotrophic factors and their receptors are crucial for the formation of neuronal connections and for the neuronal survival during embryonic development of the nervous system. This has particularly been shown by studies of the PNS. READ MORE

  4. 14. Neurotrophic signalling by GDNF and its receptors

    Author : Miles Trupp; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Many investigators have sought a polypeptide which would alleviate the neuronal loss associated with Parkinson's disease--specifically dopaminergic neurons of the ventral mesencephalon. The survival of this population of neurons has been known for some time to be promoted by soluble factors present in the conditioned media of glial cell lines. READ MORE

  5. 15. Central nervous modulation of pain - a clinical and experimental study

    Author : Christopher Lundborg; Göteborgs universitet; []
    Keywords : pain; head and neck; cisterna magna; baroreflex; noradrenaline; GDNF; co-cultured astrocytes; naloxon; osteoarthritis; calcium;

    Abstract : This series of studies addresses several conceptual issues in modern pain therapy related to the contemporary understanding of mechanisms and modulators involved in the pain sensation. Novel invasive therapy for severe pain, neurogenic interactions, humoral regulators and cellular responses were studied. READ MORE