Search for dissertations about: "glioblastoma multiforme treatment thesis"

Showing result 21 - 24 of 24 swedish dissertations containing the words glioblastoma multiforme treatment thesis.

  2. 21. Modeling Neural Stem Cell and Glioma Biology

    Author : Tobias Bergström; Karin Forsberg-Nilsson; Staffan Johansson; Sven Påhlman; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; neural stem cell; integrins; glioma; PDGF; mast cell; Molekylär cellbiologi; Molecular Cellbiology; Oncology; Onkologi;

    Abstract : This thesis is focused on neural stem cell (NSC) and glioma biology. I discuss how NSCs interact with extracellular matrix (ECM) proteins in the stem cell niche, and investigate the consequences of deregulated Platelet-derived growth factor (PDGF) signaling for embryonic NSCs in transgenic mice. READ MORE

  4. 22. Synergistic effects of mesenchymal stromal cells and immunotherapy in experimental brain tumors

    Author : Salina Gunnarsson; Neurokirurgi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; mesenchymal stromal cells; rat; IFNγ; IL-7; immunotherapy; glioma;

    Abstract : Glioblastoma multiforme (GBM) is the most common and aggressive form of primary brain tumor. In spite of surgical resection, combined radiation therapy and chemotherapy, the mean survival is less than 15 months following diagnosis. READ MORE

  5. 23. Epigenetic mechanisms and regulatory aspects of human cancer and neural progenitor cells : implications for diagnosis and therapy

    Author : Monira Akhtar; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Epigenetic is defined as heritable modification or properties of the functional genome that are not directly embedded in the DNA sequence. Epigenetic changes include DNA methylation, histone modifications and RNA-mediated gene silencing. READ MORE

  6. 24. Identification of compounds that target glioma initiating cells

    Author : Shimei Wee; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Glioblastoma multiforme is a common form of brain tumor that leads to debilitating effects despite the current regiment of treatment, which includes surgery, chemotherapy and radiotherapy. With the discovery of glioma-initiating cells (GICs) that exists within the bulk tumor, some light has been shed on this disease. READ MORE