Search for dissertations about: "glioma radiology"

Showing result 1 - 5 of 12 swedish dissertations containing the words glioma radiology.

  2. 1. Preoperative MRI and PET in suspected low-grade gliomas : Radiological, neuropathological and clinical intersections

    Author : Anna Falk Delgado; Elna-Marie Larsson; Anja Smits; Jens Sörensen; John Hald; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Low-grade glioma; MRI; PET; FA; MD; Perfusion; Diffusion; Neuropathology; Oligodendroglioma; Astrocytoma; PET; tractography; DTI; DTT; Radiologi; Radiology;

    Abstract : Background: Gliomas are neuroepithelial tumours classified by cell type and grade. In adults, low-grade gliomas are comprised mainly of astrocytomas and oligodendrogliomas grade II. READ MORE

  4. 2. Significance of white matter anatomy in interpreting features and behaviour of low-grade gliomas and implications for surgical treatment

    Author : Francesco Latini; Mats Ryttlefors; Lorenzo Bello; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; White matter; Cerebral gliomas; DTI; Brain-Grid; Brain mapping; Human connectome project; Anatomi; Human Anatomy; Oncology; Onkologi; Neurokirurgi; Neurosurgery; Radiology; Radiologi; Neurology; Neurologi;

    Abstract : Diffuse gliomas are extremely heterogeneous tumours characterized by slow growth but extensive infiltration. Their kinetic features reflect the complex interaction over time with the surrounding brain, influencing treatment planning and outcome. READ MORE

  5. 3. Proton Magnetic Resonance Spectroscopy in Brain Tumors - Clinical Applications

    Author : Isabella Björkman-Burtscher; Lund Diagnostisk radiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; radiology; Clinical physics; Localization; Abscess; Brain; Tumor; Spectroscopy; Magnetic Resonance; tomography; medical instrumentation; Klinisk fysiologi; radiologi; tomografi; medicinsk instrumentering;

    Abstract : Aims: · to present a test phantom and test method for evaluation of proton magnetic resonance spectroscopy (1H-MRS) single volume localization techniques regarding signal contamination; · to describe the introduction of 1H-MRS in the daily routine of a standard MR-unit; · to evaluate the possibilities offered by 1H-MRS to improve preoperative diagnostic accuracy in patients scheduled for stereotactic biopsy of intracranial mass lesions; · to evaluate the possibilities offered by 1H-MRS to improve diagnostics and therapy control in patients with brain abscesses; · to test the hypothesis that 1H-MRS might be useful for differentiation of brain tumors, based on metabolic changes in tissue across brain lesions or surrounding tissue. Results and conclusions: · The test phantom and test method allow quality assessment with good reproducibility. READ MORE

  6. 4. Tumour Targeting Using Radiolabelled EGF Conjugates : Preclinical Studies

    Author : Åsa Liljegren Sundberg; Jörgen Carlsson; Lars Gedda; Vladimir Tolmachev; Erik Blomquist; Gregory P. Adams; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Radiation sciences; targeting; tumour; EGF; radionuclide; gefitinib; Iressa; ZD1839; glioma; therapy; diagnostics; Strålningsvetenskap; Radiation biology; Strålningsbiologi;

    Abstract : Tumour targeted radiotherapy is an appealing approach for treatment of disseminated tumour cells. A targeting agent that specifically binds to a structure on tumour cells is then used to transport therapeutically relevant radionuclides. The epidermal growth factor receptor, EGFR, is overexpressed on tumour cells in several malignancies, e.g. READ MORE

  7. 5. MRI at 3 T of brain functions and fibre tracts adjacent to intracranial tumors

    Author : Danielle van Westen; Lund Diagnostisk radiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; medical instrumentation; Klinisk fysiologi; radiologi; tomografi; medicinsk instrumentering; radiology; tomography; Clinical physics; Medicin människa och djur ; Medicine human and vertebrates ; somatosensory cortex; diffusion magnetic resonance imaging; neoplasms; Functional Magnetic Resonance Imaging;

    Abstract : The aims of the studies were: to evaluate the spatial resolution of fMRI at 3 T by studying fingersomatotopy in area 3 b of the primary sensory area (Paper 1); to investigate the potential of fMRI at 3T as a clinical tool for preoperative evaluation of patients with intracranial tumors (Paper 2); to investigate the effect of glioma resection on the spatial extent of fMRI activation as compared to the normal within-subject variability (Paper 3); to determine whether the apparent diffusion coefficient (ADC) and fractional anisotropy (FA) can distinguish tumor-infiltrated edema of gliomas from pure edema of meningiomas and metastases (Paper 4). Results: Strict somatotopic organisation in the primary sensory cortex was shown in the group average; at the subject level the thumb was located laterally, anteriorly and inferiorly to the little finger in 94 % of subjects (Paper 1). READ MORE