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Found 5 swedish dissertations matching the above criteria.

  1. 1. Evaluation of neurotoxic properties of gliotoxin

    Author : Viktoria Axelsson; Anna Forsby; Marion Ehrich; Stockholms universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; mycotoxin; gliotoxin; A. fumigatus; cytotoxicity; neurotoxicity; Neurochemistry; Neurokemi;

    Abstract : The occurrence of mould in food and animal feed is a severe problem due to the secondary metabolites, called mycotoxins, which can possess toxic activity. Aspergillus fumigatus is a common fungus found in improperly stored animal feed and the abundance of spores of the fungus is frequently spread into the air. READ MORE

  2. 2. Analysis of Secondary Metabolites from Aspergillus fumigatus and Penicillium nalgiovense : Antimicrobial Compounds from Filamentous Fungi Isolated from Extreme Environments

    Author : Stefan Svahn; Lars Bohlin; Björn Olsen; Ulf Göransson; Erja Chryssanthou; Douglas Kinghorn; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Aspergillus fumigatus; Penicillium nalgiovense; secondary metabolites; invasive aspergillosis; elicitation; gliotoxin; bis methyl gliotoxin; amphotericin B; Pharmacognosy; Farmakognosi;

    Abstract : This thesis describes the cultivation and extraction of filamentous fungi isolated from extreme environments in the search for new antibiotic compounds. Filamentous fungi are a rich source of medicines including antibiotics, and it is believed that many currently unknown fungal species and bioactive fungal metabolites remain to be discovered. READ MORE

  3. 3. Invasive fungal disease in immunocompromised hosts with focus on diagnostics

    Author : Helena Hammarström; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; invasive fungal disease; diagnosis; 1; 3-β-d-glucan; hematological malignancies; hematopoietic stem cell transplantation; HIV; lung transplant recipients; bronchiolitis obliterans syndrome;

    Abstract : Invasive fungal diseases (IFDs) are severe conditions affecting immunocompromised patients. The primary aim of this thesis was to explore different methods for diagnosis of IFD in different groups of immunocompromised patients. Papers I and II included patients with hematologic disorders. READ MORE

  4. 4. Immunocompromised Patients. Infections, Diagnostics and Nosocomial Transmission

    Author : Anna Stjärne Asplund; Infektionsmedicin; []
    Keywords : ;

    Abstract : The aim of the work presented in this thesis was to improve the management of infections in immunocompromised patients by studying aspects of diagnostics, epidemiology and nosocomial transmission. Infection and rejection are common complications in lung-transplant patients, and early diagnosis and treatment are important for a positive outcome. READ MORE

  5. 5. Mycotoxins in indoor environments. Determination using mass spectrometry

    Author : Erica Bloom; Avdelningen för medicinsk mikrobiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Gas chromatography; Mass spectrometry; Mycotoxin; Indoor Air; Ergosterol.; Mold; High pressure liquid chromatography; Dust; Building materials;

    Abstract : Dampness in indoor environments may cause various health problems. The specific causative agent(s) are unknown but may originate from degradation processes in damp materials, microbial growth, or a combination of these phenomena. The health impact of dampness in buildings is a politically, legally, and economically important question. READ MORE