Search for dissertations about: "global gene expression analysis"

Showing result 1 - 5 of 151 swedish dissertations containing the words global gene expression analysis.

2. 1. Approaches to differential gene expression analysis in atherosclerosis

   Author : Tove Andersson; KTH; []
   Keywords : representational difference analysis; gene expression profiling; microarray analysis; atherosclerosis; foam cell formation;

   Abstract : Today’s rapid development of powerful tools for geneexpression analysis provides unprecedented resources forelucidating complex molecular events.The objective of this workhas been to apply, combine andevaluate tools for analysis of differential gene expressionusing atherosclerosis as a model system. READ MORE

4. 2. Weighted Analysis of Microarray Experiments

   Author : Anders Sjögren; Göteborgs universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; DNA microarray; differential expression; gene expression; quality control QC ; quality assurance QA ; quality assessment; generalised linear model; empirical Bayes; weighted moderated statistic; invalid p-value; heteroscedasticity; WAME; heteroscedasticity;

   Abstract : DNA microarrays are strikingly efficient tools for analysing gene expression for large sets of genes simultaneously. The aim is often to identify genes which are differentially expressed between some studied conditions, thereby gaining insight into which cellular mechanisms are differently active between the conditions. READ MORE

5. 3. Genomic profiling of breast cancer by microarray-based technology and bioinformatics

   Author : Johan Staaf; Bröstcancer-genetik; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Survival; Prognostic predictor; Gene Expression; ERBB2; HER2; Microarray; Copy Number Analysis; CGH; aCGH; Amplification; Gene expression analysis;

   Abstract : Cancer is a genetic disease that arises when a cell acquires unlimited growth potential through a series of mutational events, which target genes essential for normal cell control and maintenance. Breast cancer is one of the most frequent malignancies in women worldwide, and it is characterized by heterogeneous tumor biology, histological subtypes, variable prognosis and variable responsiveness to treatment. READ MORE

6. 4. Global functional association network inference and crosstalk analysis for pathway annotation

   Author : Christoph Ogris; Erik Sonnhammer; Alfonso Valencia; Stockholms universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; biological networks; genome wide functional association networks; global gene association networks; gene networks; protein networks; functional association; functional coupling; network biology pathway analysis; pathway annotation; pathway enrichment; network-based enrichment; enrichment; Biochemistry towards Bioinformatics; biokemi med inriktning mot bioinformatik;

   Abstract : Cell functions are steered by complex interactions of gene products, like forming a temporary or stable complex, altering gene expression or catalyzing a reaction. Mapping these interactions is the key in understanding biological processes and therefore is the focus of numerous experiments and studies. READ MORE

7. 5. Gene expression profiling in periodontitis

   Author : Haleh Davanian Mohaghegh; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : The chronic inflammatory disease periodontitis is characterized by destruction of periodontal tissue, i.e. the tissues that surround and support the teeth. READ MORE