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Showing result 1 - 5 of 8 swedish dissertations matching the above criteria.

  2. 1. Functional and molecular aspects of the glomerular barrier

    Author : Anna Björnson Granqvist; Göteborgs universitet; []
    Keywords : glomerular endothelium; glycocalyx; podocyte; proteoglycan; glycosaminoglycans; nephrotic syndrome;

    Abstract : The kidneys are crucial for maintaining a normal salt-water balance in the body, which is a prerequisite for life. They do that by filtering 180 liters of plasma per day across the highly permselective glomerular barrier and reabsorbing 99 % of the filtrate. READ MORE

  4. 2. Properties of the glomerular endothelial cell surface layer in vitro and in vivo

    Author : Vincent Fridén; Göteborgs universitet; []
    Keywords : Glomerular filtration; Glomerular endothelial cell surface layer; Proteinuria; Proteoglycans; glycocalyx; glycosaminoglycans; glomerular endothelial cells; permselectivity and glomerular endothelial cell coat;

    Abstract : A healthy kidney produces final urine that is practically devoid of proteins and other physiologically important solutes. Tremendous amounts of fluid are filtered every day through the glomerular filtration barrier which is the actual sieving site in the kidney. READ MORE

  5. 3. Properties of the endothelial cells and the glomerular barrier

    Author : Jenny Sörensson; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Capillary permeability; kidney glomerulus physiology; isolated perfused kidney; endothelium; orosomucoid; charge; horseradish peroxidase; inflammation; proteoglycan; cAMP.;

    Abstract : The kidneys are vital organs that filter plasma to produce 180 liters of primary urine per day. Only 1% of this volume is excreted and the rest is reabsorbed. Naturally, such huge amounts of fluid must be well controlled to maintain the homeostasis, which is a prerequisite for life. READ MORE

  6. 4. Aspects of the glomerular barrier in healthy and diabetic kidneys

    Author : Marie Jeansson; Göteborgs universitet; []
    Keywords : glomerular size and charge selectivity; isolated perfused kidney; electron microscopy; glycocalyx; diabetic nephropathy; NOD mice;

    Abstract : Each day 180 liters of plasma is filtered in the kidneys. Under normal conditions, the glomerular barrier restricts the passage of macromolecules such as albumin while it is highly permeable to water and small solutes. Proteinuria is a hallmark of renal disease and reflects impairment of the glomerular barrier. READ MORE

  7. 5. Endothelial Nitric Oxide in the Control of Glomerular Hemodynamics

    Author : János Pittner; Daniel H. Casellas; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cell biology; Juxtamedullary nephron; afferent arteriole; nitric oxide; endothelial calcium; diaminofluoresceins; fura-2; autoregulation; shear stress; flow; videomicroscopy; Cellbiologi; Cell biology; Cellbiologi; Physiology; fysiologi;

    Abstract : The afferent arteriole of the kidney is a unique vascular segment: it is the effector of the renal hemodynamic autoregulation. The use of the isolated, perfused juxtamedullary nephron preparation makes it possible to visualize the afferent arteriole while preserving its tissue surroundings and the functional integrity of the nephron. READ MORE