Search for dissertations about: "glucagon-like peptide 1"

Showing result 1 - 5 of 51 swedish dissertations containing the words glucagon-like peptide 1.

  2. 1. Central actions of glucagon-like peptide-1 on food intake and reward: Novel neurological targets and sex divergent effects

    Author : Jennifer E. Richard; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Glucagon-like peptide-1; Food reward; Food intake; GLP-1; Sex differences;

    Abstract : Obesity is one of the biggest health risks of our society; however, treatment options are sparse and often result in suboptimal weight-loss. The glucagon-like peptide-1 (GLP-1) receptor (GLP-1R) agonist liraglutide was recently approved for treatment of obesity in the US. READ MORE

  4. 2. Glucagon-like peptide-1 and alcohol-mediated behaviors in rodents

    Author : Daniel Vallöf; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Addiction; Dopamine; Gut-brain axis; Reward;

    Abstract : Alcohol use disorder (AUD) is a serious cause of morbidity and mortality. However, due to the limited efficacy of existing pharmacotherapies, further investigations of potential neurochemical targets are required to define new pharmacological interventions. READ MORE

  5. 3. The endocrine heart - metabolic actions of atrial natriuretic peptide

    Author : Amra Jujic; Kardiovaskulär forskning - hypertoni; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Atrial natriuretic peptide; type 2 diabetes; rs5068; insulin resistance; glucose dependent insulinotropic peptide; glucagon-like peptide-1; left ventricular hypertrophy;

    Abstract : Abstract The natriuretic peptides (NPs), namely atrial natriuretic peptide (ANP) and bran natriuretic peptide (BNP), which are secreted from cardiomyocytes in response to cardiac wall stress, play a significant role in the regulation of blood pressure, intravascular volume, and cardiac remodeling. Recently, NPs emerged as hormones with metabolic actions such as inhibition of the renin-angiotensin system and inhibition of inflammation, together with lipolysis and adipose tissue browning. READ MORE

  6. 4. Gastric Bypass in Morbid Obesity : Postoperative Changes in Metabolic, Inflammatory and Gut Regulatory Peptides

    Author : Camilla Holdstock; Britt Edén Engström; Anders Karlsson; Per Hellström; Uppsala universitet; []
    Keywords : LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES; gastric bypass; morbid obesity; ghrelin; C-reactive protein; pancreatic polypeptide; peptide YY; glucagon-like peptide-1; Medicine; Medicin;

    Abstract : This thesis examines the effect of surgical weight loss on gut and adipose tissue peptides involved in appetite regulation and energy homeostasis in morbidly obese humans. Roux-en-Y gastric bypass (RYGBP) is the gold standard operation used for effective long-term weight loss and improved health. READ MORE

  7. 5. Appetite-regulating peptides and natural rewards: emphasis on ghrelin and glucagon-like peptide-1

    Author : Jesper Vestlund; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Reward; Gut-brain axis; Sexual behaviors; Skilled reach foraging;

    Abstract : Evolutionary conserved natural behaviors, such as foraging and sexual behaviors, are strongly associated with reward processes. Brain areas important for reward processes include, but are not limited to, the nucleus accumbens (NAc) shell, the ventral tegmental area (VTA), the laterodorsal tegmental area (LDTg) and the nucleus of the solitary tract (NTS). READ MORE