Search for dissertations about: "glucagon"

Showing result 1 - 5 of 121 swedish dissertations containing the word glucagon.

  1. 1. Signal Transduction of Glucagon Secretion

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Elaine Vieira; Uppsala universitet.; [2006]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Cell biology; secretion; glucagon; store-operated channels; calcium; diabetes; Cellbiologi; NATURAL SCIENCES Biology Cell and molecular biology Cell biology; NATURVETENSKAP Biologi Cell- och molekylärbiologi Cellbiologi;

    Abstract : Diabetes mellitus is a bihormonal disorder with hyperglycemia due to deficiency of insulin and hypersecretion of glucagon. To improve diabetes treatment it is important to clarify the signal transduction of glucagon secretion. READ MORE

  2. 2. α-Cell signalling in glucose-regulated glucagon secretion

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Qian Yu; Uppsala universitet.; [2018]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Islets; glucagon; insulin; somatostatin; ATP; cAMP; Ca2 ; GHB; oscillations; α-cell; β-cell; δ-cell; Medical Cell Biology; Medicinsk cellbiologi;

    Abstract : Glucagon is a blood glucose-elevating hormone released from α-cells in the islets of Langerhans during hypoglycaemia. Glucagon is critical for glucose homeostasis and inappropriate regulation of its secretion underlies both impaired counter-regulation of hypoglycaemia and chronic hyperglycaemia in diabetes patients. READ MORE

  3. 3. Oscillatory Ca2+ signaling in glucose-stimulated murine pancreatic β-cells Modulation by amino acids, glucagon, caffeine and ryanodine

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Meftun Ahmed; Uppsala universitet.; [2001]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cell biology; pancreatic β-cells; islets of Langerhans; glucose; Ca2 oscillations; Ca2 transients; potassium; ryanodine; caffeine; glucagon; cAMP; inositol 1; 4; 5-trisphosphate; fura-2; glycine; alanine; arginine; Ca2 channels; rats; lean mice; ob ob mice; leptin; Cellbiologi; MEDICINE Morphology; cell biology; pathology Cell biology; MEDICIN Morfologi; cellbiologi; patologi Cellbiologi; medicinsk cellbiologi; Medical Cell Biology;

    Abstract : Oscillations in cytoplasmic Ca2+ concentration ([Ca2+]i) is the key signal in glucose-stimulated β-cells governing pulsatile insulin release. The glucose response of mouse β-cells is often manifested as slow oscillations and rapid transients of [Ca2+] i. READ MORE

  4. 4. Novel insights into the regulation of insulin secretion by GLP-1, GIP and glucagon

    University dissertation from Medicine (Lund)

    Author : Linda Ahlkvist; Lunds universitet.; Lund University.; Lunds universitet.; Lund University.; [2015]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Vagus nerve; GPR119; Insulin resistance; Glucagon; GIP; GLP-1; Insulin;

    Abstract : Popular Abstract in Swedish När vi äter socker frisätter kroppen hormonet insulin från specifika beta-celler i bukspottskörteln för att förmå muskelceller och fettceller att ta upp sockret från blodet och därmed återställa blodets sockerbalans. Vid övervikt blir dessa vävnader resistenta mot insulinets verkan vilket leder till att sockret stannar kvar i blodet. READ MORE

  5. 5. Regulation of glucagon secretion from pancreatic alpha cells

    University dissertation from Department of Clinical Sciences, Lund University

    Author : Yang De Marinis; Lunds universitet.; Lund University.; Lunds universitet.; Lund University.; Lunds universitet.; Lund University.; [2010]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Epac2; glucagon secretion; pancreatic alpha cells; K- ATP channel; N-type Ca2 channel; L-type Ca2 channel; GLP-1; cAMP; PKA; Adrenaline; PKC;

    Abstract : Glucagon secreted by pancreatic α-cells plays an important role in the regulation of blood glucose. In this thesis, different techniques such as electrophysiology, immunohistochemistry and hormone secretion assay were combined to explore the mechanisms by which glucagon secretion is regulated. READ MORE