Search for dissertations about: "glucocorticoid regulation"
Showing result 21 - 25 of 63 swedish dissertations containing the words glucocorticoid regulation.
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21. Transcription factors involved in negative and positive gene regulation by glucocorticoids
Abstract : Steroid hormones, including glucocorticoids (GCs), control a wide variety of developmental and physiological responses in higher eukaryotic organisms. They pass through the plasma membrane and bind to specific receptor proteins inside the cell. READ MORE
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22. Increased glucocorticoid sensitivity in pancreatic beta-cells : effects on glucose metabolism and insulin release
Abstract : Type 2 diabetes mellitus (T2DM) is characterized by three pathological alterations: (1) insulin resistance in peripheral tissues, (2) increased hepatic glucose production and (3) impaired insulin secretion from the pancreatic beta-cells. Glucocorticoids (GCs) exert profound effects on glucose homeostasis. READ MORE
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23. Role of nuclear receptors in the regulation of human adipose tissue metabolism
Abstract : Nuclear receptors modulate expression of genes involved in adipose tissue (AT) metabolism. Their improved understanding may provide new treatment options for metabolic disorders such as obesity, insulin resistance (IR) and type 2 diabetes (T2D). READ MORE
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24. Expression and Regulation of Neuropeptide Y (NPY) in the Islets of Langerhans
Abstract : This thesis deals with the expression, localization and regulation of neuropeptide Y (NPY) in the pancreatic islets of Langerhans under normal and experimental conditions. NPY is widely distributed in the mammalian nervous system and belongs to a family of closely related petides also comprising peptide YY (PYY) and pancreatic polypeptide (PP). READ MORE
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25. Endogenous and exogenous glucocorticoid effects in a model of allergic airway inflammation
Abstract : Allergic asthma and rhinitis are inflammatory diseases of the airways. Allergic asthma is characterized by eosinophilic inflammation, reversible bronchoconstriction and airway hyperresponsiveness, whereas patients with rhinitis suffer from nasal inflammation, leading to rhinorrhea and nasal congestion. READ MORE