Search for dissertations about: "glucocorticoid s"
Showing result 1 - 5 of 26 swedish dissertations containing the words glucocorticoid s.
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1. Molecular regulators of glucose and lipid metabolism in skeletal muscle
Abstract : Skeletal muscle is a primary site of insulin action and insulin-stimulated glucose transport and occupies a center stage in maintaining whole body glucose and lipid homeostasis. Another key feature of a healthy skeletal muscle is its ability to switch between utilization of lipids and glucose as fuel in response to feeding or fasting respectively. READ MORE
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2. Mortality and morbidity in patients with Addison's disease
Abstract : Addison's disease (AD) or primary adrenal insufficiency is a rare disease with an estimated prevalence of 100-140 per million inhabitants and deadly unless treated with glucocorticoids (GCs). Very limited information is available on the morbidity and mortality in this patient group. READ MORE
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3. Glucocorticoid receptor function : interactions, mutants and ligand responses
Abstract : The protein that is investigated in this thesis is the glucocorticoid receptor (GR), which belongs to the nuclear hormone receptor superfamily of ligand activated transcription factors. The nuclear receptors share three conserved structural domains, the N-terminal transactivating domain, the central DNA-binding domain and the C-terminal ligand-binding domain. READ MORE
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4. Functional analysis of ligand recognition by the glucocorticoid receptor
Abstract : The glucocorticoid receptor (GR) is a ligand-inducible transcription factor that belongs to the superfamily of nuclear hormone receptors. It contains three structural and functional domains. READ MORE
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5. Genetic factors in primary hypertension- with emphasis on renal sodium reabsorption
Abstract : Genetic factors are of importance for the development of primary hypertension (HT). Intrauterine growth retardation, salt sensitivity and insulin resistance are all characteristic features of individuals prone to develop HT. READ MORE