Search for dissertations about: "glucocorticoids"

Showing result 11 - 15 of 159 swedish dissertations containing the word glucocorticoids.

  2. 11. Systems Biology Based Approaches to Identify Biomarkers in Seasonal Allergic Rhinitis

    Author : Hui Wang; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Glucocorticoids; Seasonal allergic rhinitis; Biomarkers; Gene expression microarray analysis; Proteomics; Multivariate analysis; Pathway analysis;

    Abstract : Glucocorticoids (GC) are the most effective anti-inflammatory treatment for seasonal allergic rhinitis (SAR). However, a few patients with SAR show poor response to GC treatment. Hence, there is a clinical need to find biomarkers to predict and monitor treatment response. READ MORE

  4. 12. Role of nuclear receptors in the regulation of human adipose tissue metabolism

    Author : Prasad G. Kamble; Jan W Eriksson; Ingrid Dahlman; Uppsala universitet; []
    Keywords : human adipose tissue; nuclear receptors; glucocorticoids; estrogen; PPARγ; lipocalin 2; glucose uptake; lipolysis; adipogenesis; genotype-based recall;

    Abstract : Nuclear receptors modulate expression of genes involved in adipose tissue (AT) metabolism. Their improved understanding may provide new treatment options for metabolic disorders such as obesity, insulin resistance (IR) and type 2 diabetes (T2D). READ MORE

  5. 13. Effects of immunosuppressive drugs on human adipose tissue metabolism

    Author : Maria J Pereira; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cyclosporin A; tacrolimus; rapamycin; glucocorticoids; new onset diabetes after transplantation; adipocytes; insulin signalling; glucose uptake; lipolysis; lipogenesis;

    Abstract : The immunosuppressive agents (IAs) rapamycin, cyclosporin A and tacrolimus, as well as glucocorticoids are used to prevent rejection of transplanted organs and to treat autoimmune disorders. Despite their desired action on the immune system, these agents have serious long-term metabolic side-effects, including dyslipidemia and new onset diabetes mellitus after transplantation. READ MORE

  6. 14. 5-HT2A : a serotonin receptor with a possible role in joint diseases

    Author : Anders Kling; Solbritt Rantapää-Dahlqvist; Carl-Olav Stiller; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; 5-HT2A serotonin receptor; serotonin; rheumatoid arthritis; adverse drug reaction; HTR2A; glucocorticoids; klinisk farmakologi; Clinical Pharmacology;

    Abstract : BackgroundSerotonin (5-HT), an amino acid derivative and neurotransmitter, has for long been studied in relation to inflammation. It is an endogenous ligand for several different types of serotonin receptors. The serotonin receptor 5-HT2A has been reported to have a role in the pathophysiology of arthritis in animal experiment models. READ MORE

  7. 15. Addison's disease and type 1 diabetes mellitus

    Author : Dimitrios Chantzichristos; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Glucocorticoids; Early Diagnosis; Mortality; Biomarkers; Drug Prescriptions; Addison Disease epidemiology; Diabetes Mellitus; Type 1 epidemiology;

    Abstract : .... READ MORE