Search for dissertations about: "glucose and insulin regulation"

Showing result 21 - 25 of 240 swedish dissertations containing the words glucose and insulin regulation.

2. 21. Mechanism-Based Modelling of Clinical and Preclinical Studies of Glucose Homeostasis

   Author : Oskar Alskär; Maria C Kjellsson; Mats O Karlsson; Jenny Y. Chien; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; glucose homeostasis; pharmacometrics; Farmakokinetik och läkemedelsterapi; Pharmacokinetics and Drug Therapy;

   Abstract : Glucose is an important nutrient and energy source in the body. However, too high concentration in the blood is harmful and may lead to several complications developing over time. It was estimated that 5 million people in the world died from complications related to diabetes during 2015. READ MORE

4. 22. Exercising on the edge: mitochondrial and metabolic responses to intense training

   Author : Mikael Flockhart; Filip J Larsen; Eva Blomstrand; Nikolai Baastrup Nordsborg; Gymnastik- och idrottshögskolan; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Exercise; training; mitochondria; performance; glucose tolerance; proteins; oxygen uptake; metabolism; cycling; Medicin Teknik; Medicine Technology;

   Abstract : Exercise and exercise training induces several physiological adaptations that increase the oxidative capacity of the muscles and improve glucose regulation. While the positive metabolic adaptations and effects on glucose regulation after exercise and exercise training have been extensively studied, negative outcomes have not. READ MORE

5. 23. Whole grain cereal products and baseline gut microbiota composition in metabolic and appetite regulation in healthy humans - Emphasizing rye and barley

   Author : Jonna Sandberg; Avdelningen för livsmedel och läkemedel; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Obesity; Type 2 Diabetes; Whole grain; Rye; Barley; Gut microbiota; Glucose regulation; Gut fermentation;

   Abstract : The prevalence of obesity, type 2 diabetes (T2D) and cardiovascular disease (CVD) is increasing continuously worldwide. These metabolic diseases are associated with many health issues, including increased risk of depression and cognitive impairment. Whole grain (WG) has shown potential to prevent obesity, T2D and CVD. READ MORE

6. 24. Maf and Mitf transcription factors regulate pancreatic endocrine cell differentiation and function

   Author : Magdalena Mazur; Stamcellscentrum (SCC); []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; pancreas development; beta cells; insulin; MafA; MafB; Mitf; diabetes;

   Abstract : Diabetes - the imbalance in glucose homeostasis is partially caused by loss or dysfunction of pancreatic insulin producing β cells or development of insulin resistance. In Type 1 diabetes β cells are destroyed in the process of an autoimmune attack, whereas in Type 2 diabetes, islets produce insufficient amounts of insulin or the insulin cannot be used adequately. READ MORE

7. 25. Pathophysiology and treatment of defective insulin secretion in diabetes

   Author : Anders Rosengren; Diabetes - öpatofysiologi; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; pancreatic beta-cells; stem cells; genetics; exocytosis; Adra2a; PACAP; GLP-1; Physiology; Fysiologi; secreting systems; Endocrinology; diabetology; Endokrinologi; insulin secretion; Diabetes mellitus; sekretion; diabetologi;

   Abstract : Defective insulin secretion is a central feature in diabetes mellitus and results from reduced pancreatic beta-cell mass as well as aberrant beta-cell function. The pathophysiology of diabetes is incompletely known, but a strong hereditary component is suggested. READ MORE