Search for dissertations about: "glucose metabolism aging"

Showing result 1 - 5 of 9 swedish dissertations containing the words glucose metabolism aging.

  2. 1. Molecular mechanisms of aging in MTDNA mutator mice

    Author : Daniel Henry Sven Edgar; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Mitochondria are intensely studied in the field of aging. mtDNA mutator mice have a proofreading deficiency in the mitochondrial DNA polymerase POLG, which causes a large amount of point mutations to be accumulated in mitochondrial DNA. These mice have mitochondrial dysfunction and experience a range of premature aging phenotypes. READ MORE

  4. 2. Prospective and retrospective memory in normal and pathological aging

    Author : Åsa Livner; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Diabetes is a progressive disease with late complications, one of the most common being diabetic neuropathy (DN). DN can lead to serious complications and accounts for more hospitalization and higher costs than all other complications of diabetes combined. READ MORE

  5. 3. Cellular remodeling in response to nutrient exhaustion : From membrane contact sites to autophagy

    Author : Mahsa Ebrahimi; Sabrina Büttner; Cristina Mazzoni; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Aging and longevity; yeast; phosphate restriction; interorganellar communication; autophagy; MVB pathway; NVJs; lipid droplets; nutritional regimes; molekylär biovetenskap; Molecular Bioscience;

    Abstract : Adaptation to fluctuating environments is critical for cellular fitness and survival. Cells need to sense changes in their surroundings and quickly adjust cellular homeostasis and metabolism accordingly. READ MORE

  6. 4. Interorganellar connectivity : From protein to lipid homeostasis

    Author : Carlotta Peselj; Sabrina Büttner; Tim Levine; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Interorganellar connectivity; nucleus; NVJs; chronic lipid bilayer stress; glucose and phosphate exhaustion; nutritional regimes; transmembrane chaperone; IPTP; molekylär biovetenskap; Molecular Bioscience;

    Abstract : Interorganellar connectivity is fundamental for the maintenance of organellar and cellular functionality and viability. This is achieved and maintained by a complex network of signaling cascades, vesicle trafficking between organelles as well as by establishment of direct physical contact at membrane contact sites (MCS). READ MORE

  7. 5. Adipose tissue, the skeleton and cardiovascular disease

    Author : Peder Wiklund; Peter Nordström; Anna Nordström; Mats Palmér; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Men; women; regional fat mass; bone mineral density; myocardial infarction; osteocalcin; high impact; longitudinal; Epidemiology; Epidemiologi; Epidemiology; epidemiologi;

    Abstract : Cardiovascular disease (CVD) is the leading cause of death in the Western World, although the incidence of myocardial infarction (MI) has declined over the last decades. However, obesity, which is one of the most important risk factors for CVD, is increasingly common. Osteoporosis is also on the rise because of an aging population. READ MORE