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Showing result 1 - 5 of 99 swedish dissertations matching the above criteria.

  2. 1. Islet insulin secretory patterns in diabetes and the role of UCP2

    Author : Jian-Man Lin; Valdemar Grill; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cell biology; type 1 diabetes; type 2 diabetes; NOD; GK; congenes; KKAy; human; islet; glucose; insulin release; oscillation; frequency; amplitude; oxidation; respiration; UCP2; western blot; Cellbiologi; Cell biology; Cellbiologi; medicinsk cellbiologi; Medical Cell Biology;

    Abstract : During development of type 1 and type 2 diabetes plasma insulin patterns are altered. Since the islet insulin release pattern has been implicated in this development, insulin secretion from single islets was studied and linked to the islet protein levels of uncoupling protein-2 (UCP2). READ MORE

  4. 2. Retinal glucose metabolism and blood flow : Effects of photic stimulation

    Author : Lin Wang; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Physiology and anatomy; blood flow; darkness; flicker; glucose oxidation; glycolysis; lactate; light; nitric oxide; optic nerve; retina; Fysiologi och anatomi; Physiology and pharmacology; Fysiologi och farmakologi; Physiology; fysiologi;

    Abstract : Retinal glucose metabolism was investigated under different light conditions in cats,pigs and rabbits. Glycolysis and glucose oxidation in the outer and inner parts of theretina were assessed by determining arteriovenous concentration differences foroxygen, glucose and lactate, as well as local blood flow. READ MORE

  5. 3. Metabolic Effects of Growth Hormone Replacement Therapy in Adults - with Special Reference to Insulin Sensitivity

    Author : Mikael Segerlantz; Malmö Institutionen för kliniska vetenskaper; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; diabetology; secreting systems; Endocrinology; Endokrinologi; sekretion; diabetologi; cortisol replacement; lipid oxidation; glucose metabolism; glucose uptake; insulin resitance; GH; insulin sensitivity; GH deficiency;

    Abstract : A risk for premature atherosclerosis and increased cardiovascular mortality has been reported in adult patients suffering from growth hormone deficiency (GHD) and receiving conventional hormone substitution without growth hormone (GH) replacement. GHD patients are resistant to insulin, which is a potential risk factor for cardiovascular mortality. READ MORE

  6. 4. Implantation-Site Dependent Differences in Engraftment and Function of Transplanted Pancreatic Islets

    Author : Joey Lau; Per-Ola Carlsson; Leif Jansson; Carina Carlsson; Caroline Kampf; Annika Tibell; Uppsala universitet; []
    Keywords : Cell biology; Type 1 diabetes; pancreatic islets; human islets; islet transplantation; vascular engraftment; revascularization; implantation-site; microenvironment; vascular density; insulin release; pro insulin biosynthesis; glucose oxidation; Cellbiologi;

    Abstract : Transplanting pancreatic islets into the liver through the portal vein is currently the most common procedure in clinical islet transplantations for treating patients with brittle type 1 diabetes. However, most islet grafts fail within a 5-year period necessitating retransplantation. READ MORE

  7. 5. C. elegans PAQR-2 ‒ A Regulator of Membrane Homeostasis

    Author : Emma Svensk; Göteborgs universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; PAQR; LRRIG; glucose; membrane fluidity; desaturase; homeoviscous adaptation;

    Abstract : The progestin and adipoQ receptor (PAQR) protein family is characterized by a 7-transmembrane domain, and a topology reversed that of G-protein coupled receptors, i.e. the N-terminus resides in the cytoplasm. READ MORE