Search for dissertations about: "glucose smooth muscle"

Showing result 1 - 5 of 19 swedish dissertations containing the words glucose smooth muscle.

  2. 1. Role of NFAT (nuclear factor of activated T cells) in vascular smooth muscle

    Author : Lisa Berglund; Malmö Institutionen för kliniska vetenskaper; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; vascular smooth muscle; proliferation; A-285222; osteopontin; AIF-1; diabetes; vascular disease; calcium; glucose; NFAT;

    Abstract : The calcium-dependent transcription factor NFAT was first described as a key player in immune cell regulation. Since then, NFAT signaling has been shown to be crucial for normal vascular development during embryogenesis. READ MORE

  4. 2. β-Adrenergic Signalling Through mTOR

    Author : Jessica M. Olsen; Tore Bengtsson; Martin Klingenspor; Stockholms universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Glucose uptake; Brown adipose tissue; White adipose tissue; Skeletal muscle; Mechanistic target of rapamycin; Glucose transporter; Physiology; fysiologi; Physiology;

    Abstract : Adrenergic signalling is part of the sympathetic nervous system and is activated upon stimulation by the catecholamines epinephrine and norepinephrine. This regulates heart rate, energy mobilization, digestion and helps to divert blood flow to important organs. READ MORE

  5. 3. Altered expression of contractile endothelin receptors in the vascular bed

    Author : Mikael Adner; Klinisk och experimentell allergiforskning; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cardiovascular system; upregulation; transcriptional regulation; smooth muscle cells; plasticity; organ culture; Endothelin; receptor; Kardiovaskulära systemet;

    Abstract : This thesis aims at characterizing the endothelin (ET) receptors in different vascular beds of man and rat. The ET-A receptor was shown to be the only contractile ET receptor present in all vascular regions, with the exception of the rat mesenteric vein where a weak ET-B receptor-mediated contraction was seen. READ MORE

  6. 4. Foxf2 and Foxc2, two transcription factors that regulate adipocyte metabolism

    Author : Rickard Westergren; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; forkhead genes; insulin signaling; glucose metabolism; adipose tissue; angiogenesis; Foxc2; Foxf2; Irs1; insulin resistance; Ang-2;

    Abstract : Type 2 diabetes is the most common metabolic disorder today and has reached epidemic proportions in many countries. Diet-induced insulin resistance plays a central role in the development of type 2 diabetes. READ MORE

  7. 5. A novel single skeletal muscle cell in vitro motility assay : effects of aging and non-enzymatic glycosylation on myosin function

    Author : Peter Höök; Karolinska Institutet; Karolinska Institutet; []
    Keywords : In vitro motility; motility speed; aging; single muscle fiber; myosin isoform; temperature; scaling; glycation;

    Abstract : The aims of this study were to develop a single skeletal muscle fiber in vitro motility assay, and to employ the assay in order to study the effects of aging and non-enzymatic glycosylation on the mechanical properties of the motor protein myosin in an attempt to improve our understanding of the molecular mechanisms underlying the aging-related impairment in regulation of muscle function. Myosin was extracted from a millimeter short single muscle fiber segment directly onto a nitrocellulosecoated coverslip for subsequent analyses of the functional properties of the motor protein. READ MORE