Search for dissertations about: "glurp"

Found 3 swedish dissertations containing the word glurp.

  2. 1. Diversity and dynamics of Plasmodium falciparum malaria

    Author : Anna Färnert; Karolinska Institutet; Karolinska Institutet; []
    Keywords : malaria; Plasmodium falciparum; diversity; genotyping; PCR; msp1; msp2; glurp; dynamics; synchronicity; consistency; clinical protection; transmission; Tanzania; travellers;

    Abstract : The epidemiology of genetic diversity of malaria parasites in relation to clinical parameters, acquisition of immunity and malaria transmission has implications for the development and evaluation of control measures such as vaccines and drugs. The diversity and dynamics of Plasmodium falciparum infections were therefore studied with a polymerase chain reaction (PCR)-based genotyping method targeting three highly polymorphic genes coding for potential vaccine candidate antigens: the two merozoite surface proteins msp1 block 2 and msp2 and the glutamine rich protein (glurp). READ MORE

  4. 2. Antibody responses and Fc gamma receptor IIa polymorphism in relation to Plasmodium falciparum malaria

    Author : Nnaemeka C. Iriemenam; Klavs Berzins; Marita Troye-Blomberg; Philippe Deloron; Stockholms universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; malaria; Plasmodium falciparum; blood-stage; antibodies; antigens; logistic models; risk factors; age factors; merozoites; IgG subclasses; Fc gamma RIIa; single nucleotide polymorphism; ethnicity; endemicity; disease susceptibility; Immunology; Immunologi; immunologi; Immunology;

    Abstract : Immunity to asexual blood-stage of Plasmodium falciparum malaria is believed to be associated with protective antibodies of certain immunoglobulin classes and subclasses. This thesis addressed the importance of antibodies in relation to malaria infection and their effective interactions with Fc gamma receptor IIa (FcyRIIa) polymorphisms. READ MORE

  5. 3. Surface antigens in Plasmodium falciparum malaria : PfEMP1 and SURFIN4.2

    Author : Maria del Pilar Quintana Varon; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Plasmodium falciparum malaria is an infectious disease that on despite of the ongoing eradication efforts is still endemic in more than 100 countries, sometimes causing severe disease that leads to the death of around half a million people per year. Malaria pathology is tightly associated with the parasite cycle inside the human red blood cells (RBCs). READ MORE