Search for dissertations about: "glutathione disulfide"
Showing result 1 - 5 of 28 swedish dissertations containing the words glutathione disulfide.
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1. Glutathione in the brain. Studies on efflux and possible implications in neurotoxicity
Abstract : Neuronal cell death in acute insults such as stroke, trauma and epilepsy involves overactivation of glutamate receptors, calcium influx and increased formation of potentially toxic reactive oxygen species. Glutathione is a key component in the antioxidant defense system against reactive oxygen species. READ MORE
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2. Studies on hepatic glutathione transferases from rat and man : 1. A kinetic mechanism for glutathione transferase A from rat liver. 2. Transferase µ, a new form of glutathione transferase in human liver
Abstract : This study of glutathione transferases was undertaken to achieve a better understanding of the catalytic and molecular properties of various isozymes of this group of drug-metabolizing enzymes.The steady-state kinetics of purified glutathione transferase A from rat liver with glutathione (GSH) and 1,2-dichloro- 4-nitrobenzene as substrates, did not follow a simple Michaelis- Menten equation. READ MORE
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3. Glutathione metabolism of human skeletal muscle in surgical trauma
Abstract : Glutathione Metabolism of Human Skeletal Muscle in Surgical Trauma Jia-Li Luo Dissertation from the Department of Anesthesiology and Intensive Care, Huddinge University Hospital, KARO Institution, Karolinska Institutet. Stockholm, Sweden In man, muscle tissue serves as a protein reservoir which is mobilized to meet the specific metabolic needs associated with various catabolic conditions, such as surgical trauma and critical illness. READ MORE
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4. Purification and properties of glutathione reductase from liver
Abstract : The present investigation was undertaken in order to acheive an increased understanding of the molecular and catalytic properties of the flavin-containing enzyme glutathione reductase.Glutathione reductase from rat and calf liver was purified close to homogeneity, both by procedures involving standard techniques but also by procedures involving affinity chromatography on 2’, 5’-ADP Sepharose 4B. READ MORE
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5. Protein disulfide isomerase : function and mechanism in oxidative protein folding
Abstract : The formation of native intramolecular disulfide bonds is critical for the folding and stability of many secreted proteins. This process involves oxidation of protein thiols to form disulfide bonds as well as rearrangement of any non-native disulfide bonds that might form. READ MORE