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Showing result 1 - 5 of 21 swedish dissertations matching the above criteria.

  2. 1. The functional role of the MUC17-based glycocalyx

    Author : Sofia Jäverfelt; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Intestine; Glycocalyx; Membrane mucin; Host defenses;

    Abstract : Our gastrointestinal tract harbors trillions of bacteria that are chemically and spatially separated from the intestinal epithelium. Maintaining an intact mucosal barrier is essential as increased bacterial contact is associated with inflammatory bowel diseases such as Crohn´s disease. READ MORE

  4. 2. Blood pressure-dependent changes in plasma volume, glycocalyx and platelet function during anaesthesia -Clinical and experimental studies

    Author : Tor Damén; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; anaesthesia; blood pressure; hypotension; norepinephrine; haematocrit; plasma volume; atrial natriuretic peptide; glycocalyx; platelet aggregation;

    Abstract : Background: Worldwide, more than 300 million surgeries are performed each year. General anaesthesia provides the surgical patient with a state of controlled loss of sensation and awareness. It is common that general anaesthesia causes hypotension. Anaesthesia-induced hypotension is associated with haemodilution and increased plasma volume (PV). READ MORE

  5. 3. Aspects of the glomerular barrier in healthy and diabetic kidneys

    Author : Marie Jeansson; Göteborgs universitet; []
    Keywords : glomerular size and charge selectivity; isolated perfused kidney; electron microscopy; glycocalyx; diabetic nephropathy; NOD mice;

    Abstract : Each day 180 liters of plasma is filtered in the kidneys. Under normal conditions, the glomerular barrier restricts the passage of macromolecules such as albumin while it is highly permeable to water and small solutes. Proteinuria is a hallmark of renal disease and reflects impairment of the glomerular barrier. READ MORE

  6. 4. Circulating proteoglycans and glycosaminoglycans during critical illness

    Author : Axel Nelson; Anestesiologi och intensivvård; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; heparan sulphate; glycocalyx; hyaluronic acid; syndecan; permeability; antimicrobial;

    Abstract : The endothelial glycocalyx is the carbohydrate rich inner layer of the blood vessels. Important components of the glycocalyx are the proteoglycans with their attached glycosaminoglycans. READ MORE

  7. 5. Functional and molecular aspects of the glomerular barrier

    Author : Anna Björnson Granqvist; Göteborgs universitet; []
    Keywords : glomerular endothelium; glycocalyx; podocyte; proteoglycan; glycosaminoglycans; nephrotic syndrome;

    Abstract : The kidneys are crucial for maintaining a normal salt-water balance in the body, which is a prerequisite for life. They do that by filtering 180 liters of plasma per day across the highly permselective glomerular barrier and reabsorbing 99 % of the filtrate. READ MORE