Search for dissertations about: "glycogen synthesis"

Showing result 1 - 5 of 25 swedish dissertations containing the words glycogen synthesis.

  2. 1. Human glycogen synthase genes. Role in insulin resistance and hypoglycaemia

    Author : Marju Orho-Melander; diabetes och endokrinologi Genomik; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; mutation; GYS2; GYS1; glycogen synthase; glycogen; insulin resistance; hypoglycaemia; liver glycogen synthase deficiency; glycogen storage disease type 0; Type 2 diabetes; metabolic syndrome; expression; chromosome 19; 19q13.3; Endocrinology; secreting systems; diabetology; Endokrinologi; sekretion; diabetologi;

    Abstract : Effective insulin-stimulated storage of excess glucose after a meal, and its rapid mobilisation in the fasting state provide basis of glucose homeostasis. Glycogen is the macromolecular storage form of glucose and glycogen synthase (GS) is the rate-limiting enzyme in glycogen synthesis. Skeletal muscle and liver are the major depots of glycogen. READ MORE

  4. 2. Two new disorders of glycogen metabolism

    Author : Johanna Nilsson; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Glycogen; Glycogenin; Glycogenosis; Glycogen storage disease; Glycosylation; Mass spectrometry;

    Abstract : Glycogen is a polymer of glucose and serves as a source of rapidly available energy. Glycogen synthesis is initiated by autoglucosylation of glycogenin. Two glycogenin genes, GYG1 and GYG2, encode the two isoforms glycogenin-1 and -2, respectively. READ MORE

  5. 3. Studies on exercise and glycogen re-synthesis in skeletal muscles of pigs with the PRKAG3 mutation

    Author : Anna Granlund; Sveriges lantbruksuniversitet; Sveriges lantbruksuniversitet; []
    Keywords : LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES;

    Abstract : AMP-activated protein kinase (AMPK) plays an important role in the regulation of glucose and lipid metabolism in skeletal muscle. Many pigs of Hampshire origin have a naturally occurring mutation situated in the PRKAG3 gene which encodes a muscle-specific isoform of the AMPK γ3-subunit. READ MORE

  6. 4. Liver regeneration : With reference to malnutrition and growth factors

    Author : Stefan Skullman; Linköpings universitet; []
    Keywords : cholecystokinin; energy substrates; epidermal growth factor; insulin-like growth factor I; liver composition; liver regeneration; malnutrition; pancreaticobiliary diversion; protein synthesis; rat; transfonning growth factor alpha; MEDICINE; MEDICIN;

    Abstract : The liver has a unique capacity to regenerate after damage, irrespective of cause. The regulatory mechanisms of this regeneration are not fully known. Liver regeneration· is associated with rapid growth and thereby increased demands for energy and synthesis of new compounds. READ MORE

  7. 5. Glucose metabolism in patients with exocrine pancreatic adenocarcinoma

    Author : Johan Permert; Linköpings universitet; []
    Keywords : endocrine pancreatic function; euglycemic hyperinsulinemic clamp; exocrine pancreatic adenocarcinoma; glucose metabolism; glyccogen synthesis; hyperglycemic clamp; immunohistochemistry; insulin resistance; insulin secretion; in situ hybridization; islet amuyloid polypeptide IAPP ; radioimmunoassay; subtotal pancreatectomy; MEDICINE; MEDICIN;

    Abstract : Carc.inoma of the exocrine pancreas is the fifth leading cause of cancer death in the Western world and the survival rate is one of the lowest for cancers of any site. Pancreatic cancer is characterized by pronounced, early cachexia and frequent metabolic complications. READ MORE