Search for dissertations about: "glycoproteomics"

Found 4 swedish dissertations containing the word glycoproteomics.

  1. 1. Targeting the human glycoproteome: new enrichment protocols and mass spectrometric analyses reveal unique and novel glycosylation sites

    Author : Adnan Halim; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Glycobiology; Glycoproteomics; Mass Spectrometry;

    Abstract : Glycosylation is one of the most common and structurally diverse posttranslational modifications of proteins. Given that protein glycosylation is involved in various cellular processes, the characterization of site-specific N- and O-linked glycosylations is becoming increasingly important. However, current mass spectrometry-based technologies, i.e. READ MORE

  2. 2. Gastrointestinal norovirus infections and the development of the next generation of mucosal vaccines

    Author : Inga Rimkute; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; human norovirus; gastrointestinal infection; mucosal vaccine; subcomponent vaccine; human intestinal enteroids; histo-blood group antigens; lipidomics; glycoproteomics; glycosphingolipids;

    Abstract : Human norovirus (HuNoV) is the causative agent of the winter vomiting disease and the leading cause of outbreaks of gastrointestinal infections across all settings and age groups in the world. The virus is highly contagious making outbreaks difficult or often impossible to control and having a high impact on societal costs and resources. READ MORE

  3. 3. Mass spectrometry for comparative proteomics of degenerative and regenerative processes in the brain

    Author : Carina Sihlbom; Göteborgs universitet; []
    Keywords : glycoproteomics; quantitative proteomics; glycoprotein; protein quantification; glycosylation; Fourier transform ion cyclotron mass spectrometry; cerebrospinal fluid; Alzheimer s disease; neurodegeneration; neuroregeneration; hippocampus; astrocytes; brain injury; 14-3-3 protein; isoform;

    Abstract : Biological processes involve changes at the protein level. Proteomics aims to determine protein changes from a normal state, to measure for instance recovery or disease progression. Mass spectrometry is the most important tool for identification of proteins and determination of post-translational modifications such as glycosylation. READ MORE

  4. 4. Mass spectrometric analyses of proteoglycans - Novel tools for studying prohormones in insulin-producing cells

    Author : Mahnaz Nikpour; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; proteoglycan; glycosaminoglycan; mass spectrometry; secretory granule; prohormones; CRISPR Cas9;

    Abstract : Proteoglycans (PGs) are proteins that carry one or more negatively charged glycosaminoglycan (GAG) chains. Proteoglycans have been identified in essentially all multicellular organisms, and are implicated in a wide range of biological and pathological processes. READ MORE