Search for dissertations about: "glycoside synthesis"

Showing result 1 - 5 of 23 swedish dissertations containing the words glycoside synthesis.

  2. 1. Asymmetric Synthesis of C-Glycosylated Amino Acids : Incorporation in Collagen Glycopeptides and Evaluation in a Model for Rheumatoid Arthritis

    Author : Tomas Gustafsson; Jan Kihlberg; Umeå universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Total synthesis; stereoselective synthesis; chiral glycine templates; Evan’s alkylation; asymmetric hydrogenation; alpha-amino acid synthesis; C-glycoside; rheumatoid arthritis; MHC; T cell; Organic chemistry; Organisk kemi;

    Abstract : This thesis describes stereoselective syntheses of four amino acids, three of which are C-glycosidic analogues of glycosylated amino acids. The overall goal of the project was to probe the interactions between MHC molecules, glycopeptide antigens and T cell receptors, that are essential for development of collagen induced arthritis. READ MORE

  4. 2. Enzymatic Synthesis of Alkyl Glycosides. New Applications for Glycoside Hydrolases

    Author : David Svensson; Bioteknik; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; CGTase; cyclodextrin glycosyltransferase; alkyl glycoside; enzyme stabliity; enzymatic synthesis; enzyme immobilisation; surfactant; glycosylation;

    Abstract : The environmental problems caused by human interventions, such as the consumption of non-renewable resources and the emission of greenhouse gases are well-recognised. Calls have been made for immediate measures to develop more sustainable society worldwide. READ MORE

  5. 3. Synthesis of xyloglucan oligo- and polysaccharides with glycosynthase technology

    Author : Fredrika Gullfot; Harry Brumer; Tuula Teeri; Jerry Ståhlberg; Mats Martinelle; KTH; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; glycosynthase; xyloglucan; xyloglucan endo-transglycosylase; retaining glycoside hydrolase; xyloglucanase; polysaccharide synthesis; Bioengineering; Bioteknik; Enzyme engineering; Enzymteknik; Bioorganical synthesis; Bioorganisk syntes; Biomaterials; Biomaterial;

    Abstract : Xyloglucans are polysaccharides found as storage polymers in seeds and tubers, and as cross-linking glycans in the cell wall of plants. Their structure is complex with intricate branching patterns, which contribute to the physical properties of the polysaccharide including its binding to and interaction with other glycans such as cellulose. READ MORE

  6. 4. Solid-phase glycoconjugate synthesis : on-resin analysis with gel-phase ¹9F NMR spectroscopy

    Author : Mickael Mogemark; Umeå universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Organic chemistry; Solid-phase synthesis; protective groups; linkers; monitoring; gel-phase; 19F NMR spectroscopy; carbohydrates; oligosaccharides; glycopeptides; Organisk kemi; Organic chemistry; Organisk kemi;

    Abstract : An efficient and versatile non-destructive method to analyze the progress of solid-phase glycoconjugate synthesis with gel-phase 19F NMR spectroscopy is described. The method relies on use of fluorinated linkers and building blocks carrying fluorinated protective groups. READ MORE

  7. 5. Novel Retaining Glycoside Hydrolases : Potential candidates for transglycosylation and hydrolysis

    Author : Zubaida Gulshan Kazi; Bioteknik; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; glycoside hydrolase; transglucosylation; alkyl glycoside; cyclodextrin glucanotransferase; Rhodothermus marinus; xylanases; hydrolysis; beta-glucosidases;

    Abstract : Our society is moving towards renewable resources, where biomass, rich incarbohydrates, is producing chemicals and fuel. However, there are severallimitations when it comes to valorisation of the carbohydrates from renewablebiomass. READ MORE