Search for dissertations about: "glycosylation"

Showing result 21 - 25 of 166 swedish dissertations containing the word glycosylation.

  1. 21. Glycoconjugates Solid-phase synthesis and biological applications

    University dissertation from Umeå : Kemi

    Author : Fredrik Wallner; Umeå universitet.; [2005]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Glycoconjugate; Glycolipid; Solid-phase synthesis; Glycosylation; Gel-phase 19F-NMR spectroscopy; Fluorinated linker; Carbohydrat array; CD1; NATURAL SCIENCES Chemistry Organic chemistry; NATURVETENSKAP Kemi Organisk kemi;

    Abstract : Glycoconjugates are biologically important molecules with diverse functions. They consist of carbohydrates of varying size and complexity, attached to a non-sugar moiety as a lipid or a protein. Glycoconjugate structures are often very complex and their intricate biosynthetic pathways makes overexpression difficult. READ MORE

  2. 22. Streptococcus pyogenes secreted enzymes interacting with the human host

    University dissertation from BMC Biomedical Centre, Lund University

    Author : Mattias Collin; Lunds universitet.; Lund University.; [2001]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; RNA fingerprinting; Streptococcus pyogenes; Clinical biology; immunoglobulins; Klinisk biologi; autoimmunity; endoglycosidase; cysteine proteinase; glycosylation;

    Abstract : Streptococcus pyogenes is one of the most common bacteria infecting humans. One of the factors contributing to the disease-causing properties is the secreted streptococcal cysteine proteinase, SpeB, which degrades several host proteins in connective tissue and circulation. READ MORE

  3. 23. Synthesis of Orthogonally Functionalized Oligosaccharides for Self-assembled Monolayers and as Multimodal Tools in Chemical Biology

    University dissertation from Linköping : Linköping University Electronic Press

    Author : Timmy Fyrner; Linköpings universitet.; Linköpings universitet.; [2012]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Oligosaccharide synthesis; glycosylation; thioglycosides; orthogonally protected; oligo lactosides ; spacer molecule; heterobifunctional; surface plasmon resonance; lipid anchor; self-assembled monolayers; glyconanoparticles;

    Abstract : This thesis covers different topics in the field of synthetic organic chemistry combined with the field of surface science and glycobiology.First, the text presents a series of orthogonally protected oligosaccharides (tri-, penta-, and heptasaccharides) of varying length and structures, which are synthesized with the aim of developing novel heterobifunctional biocompatible cross-linkers. READ MORE

  4. 24. Structural and functional analyses of infectious pancreatic necrosis virus (IPNV)

    University dissertation from Department of Microbiology, Lund University

    Author : Anna Hjalmarsson; Lunds universitet.; Lund University.; [1999]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; cellular localisation; glycosylation; VP3-RNA cores; virus-specified components; immuno dot blot; TCID50; IPNV; purification; Microbiology; bacteriology; virology; mycology; Mikrobiologi; bakteriologi; virologi; mykologi;

    Abstract : Infectious pancreatic necrosis virus (IPNV) is a naked virus of an uncomplicated structure. In the interior part of the virion, the two segments of double-stranded RNA are located together with the minor structural protein VP1. This protein is detected in its free form as well as linked to the genome. READ MORE

  5. 25. Multimodal Interaction Chromatography for the Investigation and Separation of Proteins

    University dissertation from Department of Microbiology, Lund University

    Author : Kristian Kallberg; Lunds universitet.; Lund University.; [2013]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Hydrophobic interaction chromatography; Multimodal chromatography; Glycosylation; Antibody; Hemoglobin; Protein purification.;

    Abstract : Minor structural changes on the surface of proteins can have tremendous impact on their biological properties. When producing therapeutic proteins it is therefore important to verify that the generated protein is the desired one. READ MORE