Search for dissertations about: "glycyrrhetinic acid"

Found 2 swedish dissertations containing the words glycyrrhetinic acid.

  2. 1. Inhibition of 11 ß-HSD. Hemodynamic and hormonal response induced by liquorice

    Author : Helga A Sigurjónsdóttir; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; 11 ß-hydroxysteroid dehydrogenase; glycyrrhetinic acid; liquorice; hypertension; gender; androgen hormones;

    Abstract : Introduction: The enzyme 11 ß-hydroxysteroid-dehydrogenas (11 ß-HSD) type 2 that converts the active hormone cortisol to the inactive cortisone is inhibited by glycyrrhetinic acid (GA), the active substance in liquorice. This leads to hypertension, hypokalaemia and sodium- and fluid retention, the syndrome of pseudo-hyperaldosteronism. READ MORE

  4. 2. Functional analysis of the proteasome in eukaryotic organisms

    Author : Marianthi Sakellari; Efstathios S. Gonos; Allan Sirsjö; Richard G. A. Faragher; Örebro universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Proteasome; Proteasome activation; Protein synthesis inhibition; Hsp70; Hsp90; Proteostasis; Aging; Alzheimer’s disease; Caenorhabditis elegans; Lifespan extension; SKN-1;

    Abstract : Proteasome degradation machinery is responsible for the turnover of a huge variety of normal and abnormal proteins, thus regulating a plethora of cellular processes. Aging is an inevitable biological process that is characterized by reduced proteasome function that leads to proteotoxic stress. READ MORE