Search for dissertations about: "gp 130"

Found 4 swedish dissertations containing the words gp 130.

  2. 1. Regulation of neurotrophic signaling molecules in motor neurons, primary sensory neurons and target tissues in senescence

    Author : Yu Ming; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Aging; dorsal root ganglion; spinal cord; muscle; neurotrophins; GFRalpha; Ret; FGF-2; gp 130; CNTF; LIF; IL-6; receptors; protein; mRNA; glia; axon dystrophy; demyelination.;

    Abstract : A hallmark of senescence is sensorimotor impairment, characterized by gait disturbance, deficits in postural control, and muscle weakness. The object of this thesis work was to elucidate some of the molecular basis underlying these disturbances, mainly referring to the occurrence of characteristic changes in gene-expression pattern, especially, alterations in trophic signaling associated with the phenotypic changes seen in motoneurons as well as primary sensory neurons and target muscles during aging. READ MORE

  4. 2. Accumulation and Composition of Gully Pot Sediments under Varying Anthropogenic Activities

    Author : Haoyu Wei; Lian Lundy; Maria Viklander; David Butler; Luleå tekniska universitet; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Catch basin; Stormwater; Sediment; Urban runoff; Xenobiotics; Gully pot maintenance; Emerging pollutant; VA-teknik; Urban Water Engineering;

    Abstract : Gully pots (GPs) are an integral urban drainage component, contributing to conveying runoff from urban surfaces and reducing the load of solids and associated contaminants entering downstream piped systems and receiving waters. Over time, the silting-up of GPs impairs their hydraulic performance, increasing the risk of GP blockage-induced flood events and reducing solids retention performance. READ MORE

  5. 3. Impact of Interleukin-6 family cytokine signalling on human endothelial cells and platelets

    Author : Madelene Lindkvist; Magnus Grenegård; Liza Ljungberg; Alistair W. Poole; Örebro universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; gp130 signalling cytokines; inflammation; transsignalling; JAK STAT; MEK ERK; PI3K AKT; platelet aggregation; vasodilation;

    Abstract : Endothelial cells lining the luminal side of blood vessels creates a barrier between the circulating blood and the extracellular matrix. Endothelial cells have important functions in regulation of vessel tension and inflammation. READ MORE

  6. 4. Toward Energy-efficient Physical Vapor Deposition : Routes for Replacing Substrate Heating during Magnetron Sputtering by Employing Metal Ion Irradiation

    Author : Xiao Li; Grzegorz Greczynski; Ivan Petrov; Lars Hultman; Jyh-Wei Lee; Linköpings universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; PVD; Magnetron sputtering; Thin films; HiPIMS; TiAlN; Energy efficiency;

    Abstract : In this Thesis, magnetron sputtering is perfected as an environmental-friendly deposition technique. I performed systematic studies of a novel approach - hybrid high-power impulse and dc magnetron co-sputtering (HiPIMS/DCMS) with metal-ion-synchronized substrate bias pulses. READ MORE