Search for dissertations about: "gpx"

Showing result 1 - 5 of 8 swedish dissertations containing the word gpx.

  2. 1. Selenoproteins in the Bovine Mammary Gland. Regulation of mRNA and Protein Expression

    Author : Katharina Bruzelius; Tillämpad biokemi; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Livsmedelsteknik; Food and drink technology; metabolism; Biokemi; Metabolism; Biochemistry; Naturvetenskap; milk; Natural science; cancer; prolactin; insulin; hydrocortisone; retinoic acid; MAC-T; northern blot; two-dimensional electrophoresis; bovine mammary gland; selenium; selenoprotein;

    Abstract : Selenium is a micronutrient that is essential for many important life processes due to the action of the specific selenoproteins containing one or more of the 21st amino acid, selenocysteine. Twenty-five selenoprotein genes have been found in the human genome but the function of many of them is not yet known. READ MORE

  4. 2. Targeting glutathione peroxidases : identifying environmental modulators, and screening for novel small molecule inhibitors

    Author : Dorian M. Cheff; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Glutathione peroxidases (GPXs) are a family of selenoproteins that are critical regulators of reactive oxygen species (ROS) in the cell, specifically hydroperoxides like hydrogen peroxide (H2O2). ROS are important for normal cell signaling and are tightly controlled to promote cell growth, proliferation, and survival. READ MORE

  5. 3. Role of oxidative stress and antioxidants in domestic and non-domestic cat spermatozoa : with special reference to cryopreservation

    Author : Paweena Thuwanut; Sveriges lantbruksuniversitet; Sveriges lantbruksuniversitet; []
    Keywords : LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES;

    Abstract : Living cells, including spermatozoa, stored under aerobic conditions require oxygen to support their normal metabolism. Excessive levels of metabolites (reactive oxygen species; ROS) can cause cell damage or lipid peroxidation. The ROS and lipid peroxidation can be detected during preparation and cryopreservation of mammalian spermatozoa. READ MORE

  6. 4. Regulation of apoptosis in the thyroid epithelium

    Author : Abeba Demelash; Göteborgs universitet; []
    Keywords : Thyroid; Apoptosis; Caspase; Calpain; Hydrogen peroxide; TGF-beta; Staurosporine; Selenium; Cytochrome c;

    Abstract : Apoptosis or programmed cell death allows the multicellular organism to remove cells that are in excess or potentially dangerous. Apoptosis has to be strictly controlled, yet inappropriately activated or suppressed apoptototic may contribute to a variety of diseases, including cancer, autoimmune disorders and neurodegenerative conditions. READ MORE

  7. 5. Yolk sac morphology and uterine blood flow are associated with fetal outcome in diabetes pregnancy

    Author : Sheller Zabihi; Uppsala universitet; []
    Keywords : Diabetes; yolk sac; embryo; gene expression; blood flow; folic acid; SOD; apoptosis;

    Abstract : Women with pregestational diabetes have a 3-5 times increased risk of giving birth to malformed babies compared with non-diabetic women. The malformations are likely to be induced before the seventh week of pregnancy, when the yolk sac is partly responsible for the transfer of metabolites to the embryo, and the uterine blood flow to the implantation site determines the net amount of nutrients available to the conceptus. READ MORE