Search for dissertations about: "granule"

Showing result 1 - 5 of 188 swedish dissertations containing the word granule.

  2. 1. Tableting performance of dry granulated particles : Significance and assessment of compression mechanical properties

    Author : Maryam Tofiq; Göran Alderborn; Ann-Sofie Persson; Josefina Nordström; Peter Kleinebudde; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Dry granulation; Powder compression; Compression parameters; Granule composition; Granule structure; Granule strength; Granule fragmentation; Granule deformation; Tablet tensile strength; Loss of tabletability;

    Abstract : Dry granulation (DG) is often utilized as an intermediate process during tablet manufacturing, for improving flow characteristics of the powder blend and/or reducing segregation issues related to the active pharmaceutical ingredient (API). The resulting granules exhibit typically irregular shapes with rough surfaces and their mechanical properties are related to the feeding powder and the process parameters used during the DG. READ MORE

  4. 2. Eosinophil granule proteins : biochemical and functional studies

    Author : Christer Peterson; Uppsala universitet; []
    Keywords : MEDICINE; MEDICIN;

    Abstract : .... READ MORE

  5. 3. Flow and Compression of Granulated Powders : The Accuracy of Discrete Element Simulations and Assessment of Tablet Microstructure

    Author : Ann-Sofie Persson; Göran Frenning; Göran Alderborn; Marie Wahlgren; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Discrete Element Method; Granule; Flow; Angle of Repose; Discharge Rate; Shear; Rolling friction; Compression; Elastic deformation; Microstructure; Degree of compression; Tensile strength; Galenisk farmaci; Pharmaceutics;

    Abstract : Simulations are powerful and important tools for gaining insight into powder processes. Ultimately, simulations have the potential to replace experiments. Thus, accurate models and insight into the essential factors for descriptions of powder behaviour are required. READ MORE

  6. 4. β-cell dysfunction in Huntington's disease

    Author : Karl Bacos; Institutionen för experimentell medicinsk vetenskap; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; metabolism; secretion; Insulin; trafficking; R6 2 mouse; granule; exocytosis; neurodegeneration; huntingtin;

    Abstract : Huntington's disease (HD), a fatal neurodegenerative disorder, is associated with an increased risk of diabetes mellitus. The reason for this is unknown, but considering the functional similarities of neurons and the insulin secreting pancreatic β-cell, pathological mechanisms may be shared by both cell types and account for neuronal as well as endocrine dysfunction. READ MORE

  7. 5. Platelet reactions in the non-self recognition of material surfaces

    Author : Marita Broberg; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; platelet; biomaterial; adhesion; granule; P-selectin; plasma protein; blood; activation; release;

    Abstract : Every material introduced into the body in order to function in contact with a living tissue is defined as a biomaterial. Biomaterials are used throughout the world in an increasing rate to replace and augment organ functions. The insertion of an implant into the human body will initiate blood coagulation at the surface of the material. READ MORE