Search for dissertations about: "growth-inhibition"

Showing result 16 - 20 of 92 swedish dissertations containing the word growth-inhibition.

  2. 16. Neuromuscular aspects of eccentric knee extensor actions : effects of electrical stimulation, age, gender and training

    Author : Jan Seger; Alf Thorstensson; Roger Enoka; Gymnastik- och idrottshögskolan; Karolinska Institutet; Karolinska Institutet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Physiology; Fysiologi; children; concentric; eccentric; efficiency; electrical stimulation; electromyography; growth; inhibition; isokinetic; specificity; strength; training;

    Abstract : The overall aim of this thesis was to study the effects of electrical stimulation, age, gender and training on the torque- and EMG-velocity relationships during eccentric knee extensor muscle actions in man. An isokinetic custom-built dynamometer was evaluated and used throughout the thesis. READ MORE

  4. 17. Retinoids in experimental neuroblastoma therapy

    Author : Frida Ponthan; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Vitamin A; retinoids; neuroblastoma; 9-cis RA; Ro 13-6307; differentiation; apoptosis; growth inhibition; 13-cis RA; fenretinide; proton magnetic resonance spectroscopy; pharmacokinetic.;

    Abstract : Retinoids are analogues of vitamin A, with documented activity against various malignant cell types. Neuroblastoma is a childhood tumour of the sympathetic nervous system that shows a complex clinical and biological heterogeneity, often with poor outcome despite intensive multimodal therapy. READ MORE

  5. 18. To defend or to offend? : Bacterial defence and competition systems

    Author : Danna Lee; Sanna Koskiniemi; Marjan van der Woude; Uppsala universitet; []
    Keywords : bacterial defence systems; bacterial competition systems; toxin-antitoxin systems; colicin; contact-dependent growth inhibition CDI ; type VI secretion system T6SS ; Rearrangement hotspot Rhs proteins; CRISPR; horizontal gene transfer; antibiotic resistance; Salmonella; Enterotoxigenic E. coli ETEC ; probiotics; synthetic biology.;

    Abstract : Bacteria are prokaryotic microorganisms that can be found in all niches of the biosphere. Bacteria must constantly evolve in order to survive and adapt to their environments. Defence systems and competition systems play a vital role in ensuring the survival of bacteria. READ MORE

  6. 19. Global Profiling of Host Cell Gene Expression During Adenovirus Infection

    Author : Fredrik Granberg; Hongxing Zhao; Ulf Pettersson; Richard Roberts; Uppsala universitet; []
    Keywords : Genetic engineering; Adenovirus; Microarray; Gene expression; Host-virus interaction; Genteknik;

    Abstract : To investigate mechanisms involved in virus-host interactions, global changes in host gene expression were examined during infection with adenovirus type 2 (Ad2) using cDNA microarray technology. In paper I and II, transcriptional changes in HeLa cells were investigated during the early and late phase of infection, respectively. READ MORE

  7. 20. Regulation and function of the Mad/Max/Myc network during neuronal and hematopoietic differentiation

    Author : Anne Hultquist; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Genetics; Myc; Mad1; neuroblastoma; hematopoiesis; phorbol ester; retinoic acid; interferon-g; TGF-b; differentiation.; Genetik; Clinical genetics; Klinisk genetik; Pathology; patologi;

    Abstract : The Mad/Max/Myc transcription factor network takes part in the control of vital cellular functions such as growth, proliferation, differentiation and apoptosis. Dimerization with the protein Max is necessary for the Myc-family of oncoproteins and their antagonists, the Mad-family proteins, to regulate target genes and carry out their intended functions. READ MORE