Search for dissertations about: "guinea pig maximization test"

Found 4 swedish dissertations containing the words guinea pig maximization test.

  2. 1. Contact allergens in p-tert-butylphenol-formaldehyde resin

    Author : Erik Zimerson; Yrkes- och miljödermatologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Dermatology; main allergens; structure-activity relationships; identification of contact allergens; guinea pig maximization test; p-tert-butylphenol-formaldehyde resin; patch testing; venereology; Dermatologi; venereologi;

    Abstract : p-tert-Butylphenol-formaldehyde resin (PTBP-F-R) is used as a binder in many adhesive formulations and it consists of a complex mixture of substances, most of which are unknown. The resin has been reported to cause allergic contact dermatitis since the 1950s. READ MORE

  4. 2. Experimental and Clinical Studies on Contact Allergy to Diphenylmethane-4,4′-diisocyanate and Related Substances

    Author : Haneen Hamada; Yrkes- och miljödermatologi; []
    Keywords : 4; 4′-MDI; freund s complete adjuvant; Guinea pig maximization test; 4; 4 -MDA; 4; 4 -DMDA; 4; 4 -DMDI; PPD; p-phenylenediamine; 2; 4-TDI; Toluene diisocyanate; trimer; FCA; Cross-reactivity; dermal uptake; contact allergy; contact dermatitis;

    Abstract : The exposure to isocyanates is more of an occupational problem than a consumer problem. The main route of exposure is assumed to be through inhalation. Isocyanates that have high vapor pressure, such as TDI, can be airborne at room temperature. Other isocyanates such as MDI are volatile only when heated. READ MORE

  5. 3. Methylisothiazolinones. Diagnosis and prevention of allergic contact dermatitis

    Author : Birgitta Gruvberger; Malmö Institutionen för kliniska vetenskaper; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; venereology; Dermatologi; Dermatology; Prevention.; Chemical burns; Occupational dermatoses; Allergic contact dermatitis; Guinea pig maximization test; Isolation identification of contact sensitizers; Inactivation; Methylisothiazolinones; Kathon® CG; venereologi;

    Abstract : Preservatives are biologically active substances which are required in water-based products/systems to prevent growth of micro-organisms. Kathon® CG (K-CG), one of several preservatives based on 5-chloro-2-methyl-4-isothiazolinon-3-one (MCI) and 2-methyl-4-isothiazolin-3-one (MI) has been shown to be a common sensitizer in dermatitis patients. READ MORE

  6. 4. Predictive testing for contact allergy : comparison of some guinea pig and mouse protocols including dose-response designs

    Author : Helen Wahlkvist; Karolinska Institutet; Karolinska Institutet; []
    Keywords : contact allergens; contact allergy; cumulative contact enhancement test; dose-response; evaluation; Freund s complete adjuvant test; guinea pig maximization test; local lymph node assay; mouse ear swelling test; patch test; predictive testing; statistical analysis;

    Abstract : Contact allergy (delayed hypersensitivity) may develop as a result of skin exposure to contact allergens (haptens) and can lead to allergic contact dermatitis. The purpose of this study was to evaluate some predictive animal test methods for contact allergens. READ MORE