Search for dissertations about: "guinea pig"

Showing result 1 - 5 of 99 swedish dissertations containing the words guinea pig.

  1. 1. Neuropeptide Y Receptors in Human, Guinea pig and Chicken : Cloning, in vitro Pharmacology and in situ Hybridization

    Author : Sara Holmberg; Helen Cox; Uppsala universitet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neurosciences; G-protein coupled receptor; neuropeptide Y; neuropeptide Y receptor; ortholog; chicken; guinea pig; mutagenesis; receptor computer modeling; mRNA in situ hybridization; Neurovetenskap; Neurology; Neurologi; medicinsk farmakologi; Medical Pharmacology;

    Abstract : Neuropeptide Y (NPY) is known to influence a vast number of physiological and behavioral processes such as vasoconstriction, circadian rhythms, feeding, anxiety and memory. Peptides of the NPY family bind to five different cloned G-protein coupled receptor subtypes (Y1, 2, 4-6). READ MORE

  2. 2. Guinea pig osteoarthrosis : morphological and biochemical studies

    Author : Lei Wei; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Hartley guinea pigs spontaneously and reproducibly develop an arthropathy mimicking human primary osteoarthrosis. The morphological lesions first appear between 6 and 12 months of age, when it is confined to the non-meniscus-covered central compartment of the medial tibial plateau without initially involving the lateral side. READ MORE

  3. 3. Regulation of spontaneous tone in guinea pig trachea

    Author : Staffan Skogvall; Neurofysiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; tetrodotoxin; lidocaine; substance P; tachykinin; prostaglandin; indomethacin; capsaicin; neuroepithelial endocrine cells; epithelium; oxygen; oscillations; spontaneous tone; Asthma; airway smooth muscle; electrical field stimulation.; Physiology; Fysiologi;

    Abstract : Asthma is a common disease, characterized by periods of bronchoconstriction of unclear origin. This thesis examines a specific behavior of airway smooth muscle, the so-called spontaneous airway tone. It was suspected that a defect regulation of this tone may be a cause of asthmatic bronchoconstriction. READ MORE

  4. 4. Morphological and molecular changes in developing guinea pig osteoarthritis

    Author : Harald Brismar; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Osteoarthritis (OA)-an unspecific term for late joint destruction-is one of the most common causes of pain and disability in elderly. OA is characterized by destruction of articular cartilage and insufficient tissue repair. Hartley guinea pigs develop a spontaneous knee arthropathy similar to primary human knee OA. READ MORE

  5. 5. Cloning and characterization of neuropeptide Y receptors of the Y1 subfamily in mammals and fish

    Author : Paula Starbäck; Uppsala universitet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neurosciences; G-protein; neuropeptide Y; panacreatic polypeptide; neuropeptide Y receptor; ortholog; zebrafish; guinea pig; pseudogene; evolution; Neurovetenskap; Neurology; Neurologi; Neurology; neurologi;

    Abstract : Neuropeptide Y (NPY) is an abundant neurotransmitter in the nervous system and forms a family of evolutionarily related peptides together with peptide YY (PYY), pancreatic polypeptide (PP) and polypeptide Y (PY). These peptides are ligands to a family of receptors that mediate a wide range of physiological effects including stimulation of appetite. READ MORE