Search for dissertations about: "guinea-pig human"

Showing result 1 - 5 of 49 swedish dissertations containing the words guinea-pig human.

  2. 1. Neuropeptide Y Receptors in Human, Guinea pig and Chicken : Cloning, in vitro Pharmacology and in situ Hybridization

    Author : Sara Holmberg; Helen Cox; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neurosciences; G-protein coupled receptor; neuropeptide Y; neuropeptide Y receptor; ortholog; chicken; guinea pig; mutagenesis; receptor computer modeling; mRNA in situ hybridization; Neurovetenskap; Neurology; Neurologi; medicinsk farmakologi; Medical Pharmacology;

    Abstract : Neuropeptide Y (NPY) is known to influence a vast number of physiological and behavioral processes such as vasoconstriction, circadian rhythms, feeding, anxiety and memory. Peptides of the NPY family bind to five different cloned G-protein coupled receptor subtypes (Y1, 2, 4-6). READ MORE

  4. 2. Guinea pig osteoarthrosis : morphological and biochemical studies

    Author : Lei Wei; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Hartley guinea pigs spontaneously and reproducibly develop an arthropathy mimicking human primary osteoarthrosis. The morphological lesions first appear between 6 and 12 months of age, when it is confined to the non-meniscus-covered central compartment of the medial tibial plateau without initially involving the lateral side. READ MORE

  5. 3. Gastric and enteric Helicobacter species in animal models and in the human colon

    Author : Erik Sturegård; Malmö Klinisk mikrobiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; mycology; Mikrobiologi; bakteriologi; IL-10; Microbiology; bacteriology; virology; virologi; mykologi; hepatitis; colitis; IBD; inflammatory bowel disease; gastritis; animal model; mouse; guinea pig; Helicobacter ganmani; Helicobacter; Helicobacter pylori;

    Abstract : The Gram-negative genus of Helicobacter consists of many bacterial species that colonize a wide range of animal hosts. The genus can be divided into gastric species that colonize the stomach, and enteric species that preferentially colonize the colon and biliary tree of various animal hosts. READ MORE

  6. 4. Morphological and molecular changes in developing guinea pig osteoarthritis

    Author : Harald Brismar; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Osteoarthritis (OA) - an unspecific term for late joint destruction-is one of the most common causes of pain and disability in elderly. OA is characterized by destruction of articular cartilage and insufficient tissue repair. Hartley guinea pigs develop a spontaneous knee arthropathy similar to primary human knee OA. READ MORE

  7. 5. Cloning and characterization of neuropeptide Y receptors of the Y1 subfamily in mammals and fish

    Author : Paula Starbäck; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neurosciences; G-protein; neuropeptide Y; panacreatic polypeptide; neuropeptide Y receptor; ortholog; zebrafish; guinea pig; pseudogene; evolution; Neurovetenskap; Neurology; Neurologi; Neurology; neurologi;

    Abstract : Neuropeptide Y (NPY) is an abundant neurotransmitter in the nervous system and forms a family of evolutionarily related peptides together with peptide YY (PYY), pancreatic polypeptide (PP) and polypeptide Y (PY). These peptides are ligands to a family of receptors that mediate a wide range of physiological effects including stimulation of appetite. READ MORE