Search for dissertations about: "hR"

Showing result 1 - 5 of 481 swedish dissertations containing the word hR.

  2. 1. Identification of novel BRCA2-binding proteins that are essential for meiotic homologous recombination

    Author : Jingjing Zhang; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; meiosis; DSB; cancer; BRCA2; MEILB2; BRME1; HR; RAD51; DMC1; DDR;

    Abstract : Meiotic recombination is a molecular process in which the induction and repair of programmed DNA double-strand breaks (DSBs) creates genetic exchange between homologous chromosomes and thus increases genetic diversity and ensures chromosome segregation. Breast cancer susceptibility gene 2 (BRCA2) is a potent cancer suppressor and is required for DSB repair by homologous recombination (HR) in mitosis. READ MORE

  4. 2. Human Resource Management in Project-Based Organisations : Challenges, Changes, and Capabilities

    Author : Karin Bredin; Jonas Söderlund; Henrik Holt Larsen; Linköpings universitet; []
    Keywords : SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; HRM; project-based organisations; people management systems; people capability; project management; line management; HR department; project capability; personalarbete; people capability; projektledning; linjechef; HR-avdelning; projekt; HRM; projektbaserade organisationer; Business studies; Företagsekonomi;

    Abstract : This doctoral thesis addresses human resource management in project-based organisations. The aim is to explore the challenges for HRM in project-based organisations and the changes in people management systems to meet these challenges. The thesis consists of a compilation of six papers and an extended summary. READ MORE

  5. 3. Nanofluidics for Static and Dynamic DNA-Protein Interaction Studies - Repair of Double-Strand Breaks from a Single-Molecule Perspective

    Author : Robin Öz; Chalmers tekniska högskola; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Single-molecule; Protein; NHEJ; Dynamic; DNA repair; HR; Biomolecule interactions; Microscopy; Fluorescence; Nanofluidics;

    Abstract : Double-strand breaks (DSBs) is one of the most lethal forms of DNA damage. A single DSB may result in stalling of vital cellular machineries, and thus, requires immediate measures by the cell. READ MORE

  6. 4. Human Resource Management in Project-Based Organisations : Challenges and Changes

    Author : Karin Bredin; Jonas Söderlund; Johann Packendorff; Linköpings universitet; []
    Keywords : SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; HRM; project-based organisations; projectification; HR department; line manager; competence; trust; change; individual; Business studies; Företagsekonomi;

    Abstract : This thesis is about human resource management (HRM) in project-based organisations. Firms have over the last decades tended to rely increasingly on project-based structures. This process of projectification implies a changed work situation for individuals in modern organisations. READ MORE

  7. 5. Young adults with childhood-onset inflammatory bowel disease - aspects of bone mineral density, body composition and physical exercise

    Author : Gudmundur Vignir Sigurdsson; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; IBD; BMD; Body composition; Physical exercise; HR-pQCT;

    Abstract : Background: Our research group has previously shown that low bone mineral density (BMD) is common in children and adolescents with inflammatory bowel disease (IBD). However, there is limited knowledge on the development of BMD and body composition traits (skeletal muscle and body fat) in early adulthood in this patient group. READ MORE