Search for dissertations about: "haemophilia"
Showing result 16 - 19 of 19 swedish dissertations containing the word haemophilia.
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16. Pharmacometric Approaches to Improve Dose Individualization Methods in Hemophilia A
Abstract : Hemophilia A is a bleeding disorder caused by the lack of functional coagulation factor VIII (FVIII). The overall aim of this thesis was to improve dose individualization of FVIII replacement therapy in hemophilia A using pharmacometric approaches. READ MORE
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17. Determination of the overall haemostasis potential and fibrin gel permeability : method development and application in research and in clinical materials
Abstract : We have previously developed a laboratory method that may screen the Overall Haemostasis Potential (OHP) in plasma based on spectophotometric measurement of an area under the fibrin aggregation curve in citrated plasma samples to which tiny amounts of exogenous thrombin and tissue-plasminogen activator (t-PA) are added. When the fibrin aggregation curve is created, the fibrinogen originally present in plasma is gradually converted to fibrin by the generated thrombin. READ MORE
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18. Coping, pain and disability in patients with chronic inflammatory and musculoskeletal diseases
Abstract : The main interest of this study is in the behavioural and psychological aspects of adjusting to a chronic, periodically painful disease. This study focuses on the concept of coping, the modes of coping, the context of coping, and the factors related to these. READ MORE
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19. Real-time analysis of blood coagulation and fibrinolysis : new rheological and optical sensing techniques for diagnosis of haemostatic disorders
Abstract : The haemostatic system has a dual paradoxical function in the body. It should arrest bleeding whenever needed, but also keep the blood flowing in the circulatory system without any obstructing blood clots. The system is complex with maoy intertwined processes that interact to produce a fine-tuned regulation of the performance. READ MORE