Search for dissertations about: "hair cells"

Showing result 1 - 5 of 66 swedish dissertations containing the words hair cells.

  1. 1. Hair cell regeneration in vestibular epithelia : a study in an in vitro model

    Author : Mimmi Werner; Diana Berggren; Andrew Forge; Umeå universitet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Vestibular hair cell; regeneration; transdifferentiation; proliferation; utricle; rat; oto-rhino-laryngologi; Oto-Rhino-Laryngology;

    Abstract : BackgroundHair cells (HCs) are the sensory receptors in both the auditory and the vestibular organs of the inner ear. Supporting cells (SCs) are non-sensory cells embracing the HCs. Injuries of the HCs by aging, acoustic trauma or ototoxic drugs (mainly aminoglycosides, e.g. READ MORE

  2. 2. The beneficial Effects of Neural Crest Stem Cells on Pancreatic      β–cells

    Author : Anongnad Ngamjariyawat; Elena Kozlova; Leif Jansson; Jens Nielsen; Uppsala universitet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neural Crest Stem Cells; Pancreatic Islets; β-cell proliferation; β-cell survival; Cadherin; Medical Science; Medicinsk vetenskap;

    Abstract : Patients with type-1 diabetes lose their β-cells after autoimmune attack. Islet transplantation is a co-option for curing this disease, but survival of transplanted islets is poor. Thus, methods to enhance β-cell viability and function as well as methods to expand β-cell mass are required. READ MORE

  3. 3. Functional Studies of Genes Associated with Muscle Growth in Pigs and Hair Greying in Horses

    Author : Lin Jiang; Leif Andersson; Kerstin Lindblad-Toh; Gerli Pielberg; Christopher Tuggle; Uppsala universitet; []
    Keywords : NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; QTN; muscle development; IGF2; ZBED6; RNA-seq; ChIP-seq; myoblasts; pancreatic beta cells; Grey horse; melanoma; MITF; Biologi med inriktning mot molekylär cellbiologi; Biology with specialization in Molecular Cell Biology;

    Abstract : Domestic animals have become very different from their wild ancestors during domestication and animal breeding. This provides a good model to unravel the molecular mechanisms underlying phenotypic variation. In my thesis I have studied genes affecting two important traits, leanness in pigs and hair greying-associated melanoma in horses. READ MORE

  4. 4. Stem cells and development : studies on SUFU and LGR5

    Author : Maria Hölzl; Karolinska Institutet; Karolinska Institutet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP;

    Abstract : Embryonic development and cancer formation appear quite different from each other at first glance, yet they share common characteristics such as the reliance on certain signalling pathways. The Hedgehog (HH) and WNT signalling cascades play key roles in a variety of developmental processes where deregulation of these pathways result in a diversity of birth defects. READ MORE

  5. 5. The role of Lhx2 in hair follicle morphogenesis and regeneration

    Author : Gunilla Törnqvist; Leif Carlsson; Umeå universitet; []
    Keywords : NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; Cell and molecular biology; Cell- och molekylärbiologi; molecular cell biology; molekylär cellbiologi;

    Abstract : Hair is important for thermoregulation, physical protection, sensory activity, seasonal camouflage and social interactions. Hair is produced in hair follicles (HFs), complex mini-organs in the skin devoted to this task. READ MORE