Search for dissertations about: "haloalkanes"

Found 2 swedish dissertations containing the word haloalkanes.

  1. 1. A multivariate approach to QSAR

    University dissertation from Umeå : Universitet

    Author : Sven Hellberg; Umeå universitet.; [1986]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; QSAR; beta-adrenergic agents; haloalkanes; halogenated anesthetics; peptides; fractional factorial design; multivariate data analysis; principal components PC ; partial least squares PLS ;

    Abstract : Quantitative structure-activity relationships (OSAR) constitute empirical analogy models connecting chemical structure and biological activity. The analogy approach to QSAR assume that the factors important in the biological system also are contained in chemical model systems.The development of a QSAR can be divided into subproblems:1. READ MORE

  2. 2. Design of Glutathione Transferase Variants for Novel Activities with Alternative Substrates

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Abeer Shokeer; Uppsala universitet.; [2010]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURAL SCIENCES Chemistry Biochemistry; NATURVETENSKAP Kemi Biokemi; NATURAL SCIENCES Chemistry Organic chemistry; NATURVETENSKAP Kemi Organisk kemi; Biokemi; Biochemistry; Organisk kemi; Organic Chemistry;

    Abstract : Glutathione transferases (GSTs) play a pivotal role in cellular defense, since they are main contributors to the inactivation of genotoxic compounds of exogenous and endogenous origins. Directed evolution was used to improve the catalytic activities of Theta class GST T1-1 toward different substrates. READ MORE