Search for dissertations about: "haptoglobin"

Showing result 1 - 5 of 32 swedish dissertations containing the word haptoglobin.

2. 1. Haptoglobin: Biosynthesis and Evolution

   Author : Krzysztof B. Wicher; Erik Fries; John W. M. Creemers; Uppsala universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; Molecular biology; haptoglobin; cleavage; C1r-LP; evolution; vertebrate; endoplasmic; Golgi; complement; Molekylärbiologi; Molecular biology; Molekylärbiologi;

   Abstract : Haptoglobin (Hp) is a serum protein known for its ability to form a tight complex with hemoglobin (Hb) and thereby inhibiting the oxidative activity of Hb. Mammalian Hp is synthesized as a precursor (proHp) that undergoes proteolytic cleavage by a previously unidentified enzyme in the endoplasmic reticulum (ER). READ MORE

4. 2. Genetic markers in rheumatoid arthritis

   Author : Solbritt Rantapää Dahlqvist; Umeå universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Rheumatoid arthritis; family history; genetic marker; HLA B27; HLA DR4; properdin factor B; C3 complement; -antitrypsin; haptoglobin; transferrin;

   Abstract : Genetic as well as environmental factors are believed to be of importance in the etiology of rheumatoid arthritis (RA). There are a number of previous studies of genetic markers in RA, but so far no genetic linkage and only a few associations have been found. Of the associations only one (with the HLA antigen DR4) appears to be well documented. READ MORE

5. 3. Human Fetal Hemoglobin : Biochemical Characterization and Recombinant Production

   Author : Khuanpiroon Ratanasopa; Tillämpad biokemi; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; Blood substitutes; HBOCs; HbF; recombinant hemoglobin; pseudoperoxidase; ITC; haptoglobin;

   Abstract : Blood transfusion is a common medical procedure when oxygen supply in the body is impaired. However, blood transfusion is not always without risks. The uncontrolled spreading of blood borne pathogens such as HIV or hepatitis B and C virus has urged researchers to look for “blood substitutes”. READ MORE

6. 4. Recognition and Separation of Hemoglobin Variants via Molecularly Imprinted Polymers

   Author : Ka Zhang; Tillämpad biokemi; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Hemoglobin; molecularly imprinted polymers; haptoglobin; protein purification; chromatography glyceraldehyde 3-phosphate dehydrogenase; Pickering emulsion;

   Abstract : Hemoglobin (Hb) is the predominant protein in red blood cells with allosteric regulation mechanisms for delivering oxygen between the lungs and tissues. After the 1980s, concentrated research on modified Hb emerged because of the necessity for the development of a blood substitute (oxygen carrier). READ MORE

7. 5. Preterm intraventricular cerebral hemorrhage: role of cell-free hemoglobin

   Author : Alex Adusei Agyemang; Lund Pediatrik; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Intraventricular hemorrhage; Preterm birth; Haptoglobin; Alpha 1 microglobulin; cerebellar hypoplasia; periventricular white matter; cell-free hemoglobin;

   Abstract : Cerebral intraventricular hemorrhage in preterm infants continues to be a major clinical problem associated with neurodevelopmental abnormalities manifested by cognitive, behavioral, attentional, social and motor deficits. Hypothesis and aims: The central thesis is that the cytotoxicity of extravasated blood and of consequently released cell-free hemoglobin(Hb) is pivotal for the pathophysiological events causally involved in brain injury. READ MORE