Search for dissertations about: "hazard ratio"
Showing result 1 - 5 of 227 swedish dissertations containing the words hazard ratio.
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1. Estimation of hazard ratios from observational data with applications related to stroke
Abstract : The objective of this thesis is to examine some challenges that may emerge when conducting time-to-event studies based on observational data. Time-to-event (also called survival) is a setting that involves analyzing how different factors may influence the length of time until an individual experiences the event of interest. READ MORE
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2. Associations of type 2 diabetes mellitus with cancer and autoimmune diseases. A population-based epidemiological study in Sweden
Abstract : This thesis aimed to search for epidemiological evidence supporting the associations of type 2 diabetes mellitus (T2DM) with cancer and autoimmune diseases (ADs) by analysing several Swedish national registries. T2DM shares risk factors with cancer, such as obesity, diet, stress, and physical inactivity. READ MORE
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3. Interleukin 6 trans-signalling : cardiovascular risk marker or therapeutical target?
Abstract : Background: Interleukin (IL) 6 signals in two pathways. In classical signalling, essential in antimicrobial defence and tissue regeneration, IL6 binds the membrane- bound IL6 receptor (IL6R) which associates with the signal transducing receptor gp130. READ MORE
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4. Essays on the Assumption of Proportional Hazards in Cox Regression
Abstract : This thesis consists of four papers about the assumption of proportional hazards for the Cox model in survival analysis. The first paper compares the hazard ratio estimated from the Cox model to an exact calculation of the geometric average of the hazard ratio when the underlying assumption of proportional hazards is false, i.e. READ MORE
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5. Renal insufficiency, mortality and myocardial infarction
Abstract : Background: Patients with dialysis-dependent renal insufficiency (RI) have a markedly increased risk of dying or developing cardiovascular disease. Among patients who have coronary heart disease (CHD), moderate or severe RI is associated with increased mortality. READ MORE