Search for dissertations about: "heart model"

Showing result 1 - 5 of 400 swedish dissertations containing the words heart model.

  2. 1. Heart Regeneration : Lessons from the Red Spotted Newt

    Author : Nevin Witman; Jamie Morrison; Thomas Braun; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Heart; Regeneration; Newt; microRNAs; RNA editing; Molecular Biology; molekylärbiologi;

    Abstract : Unlike mammals, adult salamanders possess an intrinsic ability to regenerate complex organs and tissue types, making them an exciting and useful model to study tissue regeneration. The aims of this thesis are two fold, (1) to develop and characterize a reproducible cardiac regeneration model system in the newt, and (2) to decipher the cellular and molecular underpinnings involved in regeneration. READ MORE

  4. 2. Risk factors for incident heart failure and atrial fibrillation in an elderly population : The role of cardiac conduction and heart rate variability

    Author : Bozena Ostrowska; Carina Blomström Lundqvist; Lars Lind; Mikael Dellborg; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; incident heart failure; incident atrial fibrillation; prediction of heart failure; short P-wave duration; heart rate variability.; Cardiology; Kardiologi;

    Abstract : Heart failure (HF) and atrial fibrillation (AF) are epidemic diseases, frequently coexisting, sharing risk factors and conferring poor prognosis. Identification of individuals at high risk of HF and AF may enable early treatment and improve the prognosis. Reliable prediction models for daily clinical practice are lacking. READ MORE

  5. 3. Bridging the gap between clinical trials and clinical practice : sacubitril-valsartan in heart failure as a model

    Author : Helena Norberg; Krister Lindmark; Ellinor Bergdahl; Eva-Lotta Glader; Björn Wettermark; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Systematic implementation; healthcare quality improvement; chronic disease management; heart failure; sacubitril-valsartan; real-world population; sex differences; kardiologi; Cardiology;

    Abstract : When novel treatments prove more effective than standard therapies, a swift and effective implementation is needed to reach cost-effectiveness and to benefit eligible patients. Meanwhile, women and elderly are often under-represented in clinical trials, which creates a knowledge gap on how to optimize treatment in clinical practice. READ MORE

  6. 4. Afterload system design for functional donor heart assessment

    Author : Harry Pigot; Institutionen för reglerteknik; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; physiological modelling; cardiac afterload; heart assessment; working heart; simulation; control of physiological and clinical variables;

    Abstract : Heart transplantation is a life-saving procedure for patients with end-stage heart failure. However, conservative acceptance criteria result in most donated hearts being discarded. Enabling clinicians to assess heart function after organ procurement can pave the way for the safe use of hearts that are currently rejected. READ MORE

  7. 5. Spectral analysis of the heart rate variability : a methodological study

    Author : Urban Niklasson; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Heart-rate variability; R-R interval; cardiac autonomic function; spectral analysis; IPFM model;

    Abstract : Heart rate and other cardiovascular variables are not steady but fluctuate over time. The evolution of computer technology the last 2 decades has made detailed analysis of the fluctuations possible and has focused the attention to the information content of the variability. READ MORE