Search for dissertations about: "heat shock protein"

Showing result 1 - 5 of 104 swedish dissertations containing the words heat shock protein.

  1. 1. Exploring small heat shock protein chaperones by crosslinking mass spectrometry

    University dissertation from Department of Chemistry, Lund University

    Author : Wietske Lambert; Lunds universitet.; Lund University.; [2012]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; cross-linking; mass spectrometry; protein-protein interactions; Hsp21; BS3; DTSSP; MALDI-TOF TOF; client protein; substrate; aggregation; unfolded protein; chaperone; Small heat shock protein; crosslinking;

    Abstract : Popular Abstract in Swedish Byggstenarna av allt liv på denna planet är celler. Vår egen kropp till exempel består av ungefär 10 biljon (1013) celler. De flesta bakterier består av bara en cell. Inne i cellerna finns alla de biomolekyler som styr livet, såsom proteiner, sockerarter, lipider, och DNA. READ MORE

  2. 2. Pathophysiology of blood-brain barrier, brain edema and cell injury following hyperthermia : New role of heat shock protein, nitric oxide and carbon monoxide : an experimental study in rat using light and electron microscopy

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Hari Shanker Sharma; Uppsala universitet.; [1999]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cell biology; blood-brain barrier; heat stress; hyperthermia; brain edema; serotonin; nitric oxide; carbon monoxide; heat shock protein; glial fibrillary acidic protein; myelin basic protein; opioids; histamine; catecholamines; naloxone; indomethacin; p-CPA; electron microscopy; immunocytochemistry; Cellbiologi; MEDICINE Morphology; cell biology; pathology Cell biology; MEDICIN Morfologi; cellbiologi; patologi Cellbiologi; Human Anatomy; anatomi;

    Abstract : This thesis deals with the molecular mechanisms of hyperthermia induced brain damage in rats. The results clearly establish that hyperthermia caused by 4 h heat stress at 38° C is associated with a breakdown of the blood-brain barrier (BBB) permeability which seems to be instrumental in causing brain edema and cell injury. READ MORE

  3. 3. Heat shock proteins as vaccine adjuvants

    University dissertation from Stockholm : Wenner-Grens institut för experimentell biologi

    Author : Khaleda Rahman Qazi; Stockholms universitet.; [2005]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Heat shock protein; vaccine; adjuvant; BCG; MEDICINE Microbiology; immunology; infectious diseases Immunology; MEDICIN Mikrobiologi; immunologi; infektionssjukdomar Immunologi;

    Abstract : New efficient vaccines against infectious diseases are in demand. Some important factors impeding the vaccine development are the poor immunogenicity and the MHC restriction of the immune responses to a number of antigens. READ MORE

  4. 4. Interactions Between Small Heat Shock Proteins and Substrate Proteins Mass Spectrometric Detection of Crosslinked Peptides to Map Protein-Protein Interactions

    University dissertation from Department of Biochemistry, Lund University

    Author : Emma Åhrman; Lunds universitet.; Lund University.; [2007]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Protein-protein interactions; Small heat shock proteins; Mass spectrometric peptide mapping; Proteins; enzymology; Proteiner; enzymologi;

    Abstract : The small heat shock proteins (sHsps) are a widespread class of molecular chaperones existing in all organisms. During heat stress the sHsps protect other proteins from unfolding and aggregation. In plants the sHsps play an especially prominent part of the stress response. READ MORE

  5. 5. Combined structural methods to characterize an oligomeric small heat shock protein Hsp21

    University dissertation from Lund University, Faculty of Science, Department of Chemistry, Division of Biochemistry and Structural Biology

    Author : Gudrun Rutsdottir; Lunds universitet.; Lund University.; [2017-05]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Small heat shock proteins; chaperones; crosslinking mass spectrometry; Stable isotope labeling; quantification; small angle X-ray scattering; cryo-electron microscopy; combined structural methods; plant stress;

    Abstract : Undersökning av Hsp21 med korslänknings-masspektrometriMänniskans kropp består av ungefär 30 trillioner celler och varje cell innehåller omkring 100 000 proteiner. Föreställ dig om kroppen vore jordklotet, varje vävnad ett land och varje cell en stad. Varje stad vore då konstant som Paris i rusningstrafiken. READ MORE