Search for dissertations about: "heat shock proteins and cancer"

Showing result 1 - 5 of 19 swedish dissertations containing the words heat shock proteins and cancer.

  2. 1. Specific and nonspecific immune mechanisms in human gut : a comparative study of normal and ulcerative colitis intestine

    Author : Moorix Mo-Wai Yeung; Sten Hammarström; Marie-Louise Hammarström; Marita Troye-Blomberg; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; human intestine; ulcerative colitis; lymphoid aggregates; intraepithelial lymphocytes; lamina propria lymphocytes; γδT-cells; cytokines; IL-2; carcinoembryonic antigen; biliary glycoprotein; epithelial cells; glycocalyx;

    Abstract : The intestine, with its large mucosal surface area, digests and absorbs food nutrients and maintains a beneficial microbial flora in the colon. Local protective immune responses against intestinal pathogens ensure the survival of the individual. These immune reactions are both specific and non-specific in nature. READ MORE

  4. 2. Regulation of cellular growth and identification of stromal gene signatures in breast cancer

    Author : Sofia Winslow; Avdelningen för translationell cancerforskning; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Breast cancer; cellular stress; proliferation; PKCα; G3BP; PMP22; miR-34c; gene expression profiles; stroma;

    Abstract : Normal tissue is tightly controlled to keep a balance between reproduction and elimination of cells. In cancer, these regulated processes are disrupted, resulting in uncontrolled cell growth. Regulation of RNA stability and turnover is important to maintain cellular homeostasis and can be controlled by various mechanisms. READ MORE

  5. 3. Molecular Regulation of Inflammation and Angiogenesis in the Tumor Microenvironment

    Author : Lothar Dieterich; Anna Dimberg; Lena Claesson-Welsh; Jonas Fuxe; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; stroma; glioma; alphaB-crystallin; HSPB5; cryab; myeloid cells; Morphology; cell biology; pathology; Morfologi; cellbiologi; patologi; Cell and molecular biology; Cell- och molekylärbiologi; Molekylär medicin; Molecular Medicine;

    Abstract : Tumor growth and progression not only depend on properties of the malignant cells but are strongly influenced by the tumor microenvironment. The tumor stroma consists of various cell types such as inflammatory cells, endothelial cells and fibroblasts, which can either inhibit or promote tumor growth. READ MORE

  6. 4. Selenoproteins in the Bovine Mammary Gland. Regulation of mRNA and Protein Expression

    Author : Katharina Bruzelius; Tillämpad biokemi; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Livsmedelsteknik; Food and drink technology; metabolism; Biokemi; Metabolism; Biochemistry; Naturvetenskap; milk; Natural science; cancer; prolactin; insulin; hydrocortisone; retinoic acid; MAC-T; northern blot; two-dimensional electrophoresis; bovine mammary gland; selenium; selenoprotein;

    Abstract : Selenium is a micronutrient that is essential for many important life processes due to the action of the specific selenoproteins containing one or more of the 21st amino acid, selenocysteine. Twenty-five selenoprotein genes have been found in the human genome but the function of many of them is not yet known. READ MORE

  7. 5. Targeting Gb3 and apoptosis-related proteins to overcome cisplatin resistance

    Author : Andreas Tyler; Kjell Grankvist; Simon Ekman; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cisplatin resistance; exosomes; gb3; HSP70; the Bcl-2 family; cell research; cellforskning; Medical Cell Biology; medicinsk cellbiologi; onkologi; Oncology;

    Abstract : Background Cisplatin is used for treatment of malignant pleural mesothelioma (MPM) and non-small cell lung cancer (NSCLC) but treatment with cisplatin often leads to acquired resistance to cisplatin, resulting in poor patient survival. Globotriaosylceramide (Gb3) and multidrug resistance protein 1 (MDR1) have been associated with cisplatin resistance. READ MORE