Search for dissertations about: "hematopoietic stem cells"

Showing result 1 - 5 of 190 swedish dissertations containing the words hematopoietic stem cells.

  1. 1. Regulation of Hematopoietic Stem Cells

    University dissertation from Division of Molecular Medicine and Gene Therapy

    Author : Emma Rörby; [2014]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Hematopoiesis; hematopoietic stem cells; hematopoietic stem cell expansion; cord blood; transforming growth factor beta; Smad signaling; pigment epithelium derived factor; CD9;

    Abstract : This thesis is about the regulation of hematopoietic stem cells (HSCs) that represent rare cells residing in the bone marrow (BM) of adults. They are multipotent cells that have the capacity to differentiate to all mature cells of the blood system and have the capacity to self-renew, i.e. generate new HSCs. READ MORE

  2. 2. Towards Generation of Human Hematopoietic Stem Cells from Pluripotent Stem Cells

    University dissertation from Lund University, Faculty of Medicine, Institution of Laboratory Medicine, Division of Molecular Medicine and Gene Therapy

    Author : Roger Rönn; [2015]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Hematopoietic stem cells; pluripotent stem cells; embryonic development.; in vitro differentiation;

    Abstract : There is a pressing need for compatible Hematopoietic Stem Cells (HSCs), in high quantities and of good clinical quality, to ensure optimal treatment for patients with various blood malignancies. Pluripotent Stem Cells (PSCs) have the potential to be a source for generating HSCs. READ MORE

  3. 3. Molecular regulation of hematopoietic stem cells

    University dissertation from Hematopoietic Stem Cell Laboratory

    Author : David Bryder; [2003]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Hematologi; extracellulära vätskor; extracellular fluids; Haematology; bone marrow transplantation; cytokines; Hematopoiesis; stem cells;

    Abstract : Hematopoietic stem cells (HSCs) are ultimately responsible for the all mature blood cell production. They can primarily be found in the bone marrow (BM) at a low frequency (~0.02%). READ MORE

  4. 4. Stem cell function and organ development analysis of Lhx2 function in hematopoietic stem cells and eye development

    University dissertation from Umeå : Umeå university

    Author : Lina Dahl; Leif Carlsson; Jan-Ingvar Jönsson; [2010]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Lhx2; hematopoietic system; hematopoietic stem cell; progenitor; embryonic stem cell; embryoid body; eye development; forebrain; eye field transcription factor; MEDICINE Dermatology and venerology; clinical genetics; internal medicine Internal medicine Molecular medicine genetics and pathology ; MEDICIN Dermatologi och venerologi; klinisk genetik; invärtesmedicin Invärtesmedicin Molekylär medicin genetik och patologi ; molekylär medicin genetik och patologi ; molecular medicine  genetics and pathology ;

    Abstract : When a multicellular organism suffers damages to tissues/organs it heals itself by either substituting the lost cellular matrix by scar formation or by regenerating the lost tissue. Regeneration likely occurs by a recapitulation of the developmental process that formed the organ. READ MORE

  5. 5. Genetic modeling of the Hippo pathway in hematopoietic stem cells

    University dissertation from Lund University: Faculty of Medicine

    Author : Lina Jansson; [2012]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; stem cells; hematopoiesis; Hippo pathway; hematopoietic stem cells;

    Abstract : Hematopoiesis is the process of blood formation from a limited pool of hematopoietic stem cells (HSCs). These rare stem cells can both self-renew to maintain the HSC pool, and differentiate to continuously replenish lost blood cells. The mechanisms of HSC regulation are not fully known. READ MORE