Search for dissertations about: "hematopoietic stem cells"

Showing result 1 - 5 of 187 swedish dissertations containing the words hematopoietic stem cells.

  1. 1. Regulation of Hematopoietic Stem Cells

    University dissertation from Division of Molecular Medicine and Gene Therapy

    Author : Emma Rörby; Lunds universitet.; Lund University.; [2014]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Hematopoiesis; hematopoietic stem cells; hematopoietic stem cell expansion; cord blood; transforming growth factor beta; Smad signaling; pigment epithelium derived factor; CD9;

    Abstract : Popular Abstract in Swedish Det finns celler i vår kropp som har ett livslångt ansvar att tillverka alla blodceller. De kallas blodstamceller, eller hematopoetiska stamceller, och är en till antalet liten population celler som har den enorma kapaciteten att göra 1012 blodceller om dagen under hela vårt liv. READ MORE

  2. 2. Cellular pathways and molecular regulation of hematopoietic stem cells

    University dissertation from Hematopoietic Stem Cell Laboratory

    Author : Kristina Anderson; Lunds universitet.; Lund University.; [2007]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; β-catenin.; lineage commitment; hematopoietic stem cells; lineage priming; Wnt signaling pathway; biphenotypic cells; PAX5;

    Abstract : Hematopoietic stem cells (HSCs) are defined by their unique properties to self-renew and differentiate into all hematopoietic cell lineages. Residing in the bone marrow (BM), adult HSCs are organized in a hierarchy of cells that differ in their self-renewal and proliferative capacity. READ MORE

  3. 3. Defining Regulators of Human Hematopoietic Stem Cells

    University dissertation from Division of Molecular Medicine and Gene Therapy

    Author : Christine Karlsson; Lunds universitet.; Lund University.; Lunds universitet.; Lund University.; [2013]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; High-throughput screening; Expansion; Hematopoietic stem cell; Cord blood; RNA interference; extrinsic Signaling molecules;

    Abstract : Bone marrow transplantation (BMT) is a conceptual and elegant example of stem cell therapy, rendered possible by the dual capacity of hematopoietic stem cells (HSCs) to self-renew and differentiate. These defining features ultimately ensure the production of all blood cell lineages and simultaneous maintenance of the stem cell pool, thereby maintaining lifelong homeostasis. READ MORE

  4. 4. Cytokine Regulation of Hematopoietic Stem Cells and Lymphopoiesis

    University dissertation from Hematopoietic Stem Cell Laboratory

    Author : Natalija Buza-Vidas; Lunds universitet.; Lund University.; [2007]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; extracellular fluids; Hematologi; Haematology; Medicin människa och djur ; Medicine human and vertebrates ; lineage commitment; cytokines; lymphopoiesis; extracellulära vätskor; transplantation; hematopoietic stem cells;

    Abstract : Large numbers of blood cells need to be continuously replaced in order to sustain the crucial functions of the immune system, oxygen transport and blood clotting. The large diversity of cell types required to maintain the integrity of the blood system are all produced from blood forming or hematopoietic stem cells (HSCs). READ MORE

  5. 5. Towards Generation of Human Hematopoietic Stem Cells from Pluripotent Stem Cells

    University dissertation from Lund University, Faculty of Medicine, Institution of Laboratory Medicine, Division of Molecular Medicine and Gene Therapy

    Author : Roger Rönn; Lunds universitet.; Lund University.; [2015]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Hematopoietic stem cells; pluripotent stem cells; embryonic development.; in vitro differentiation;

    Abstract : Popular Abstract in Swedish Idag har patienter med blodcancer (leukemi) eller genetiskt betingade blodsjukdomar (sickelcellanemi etc.) begränsad tillgång till behandlingar som effektivt och riskfritt botar sjukdomstillståndet. READ MORE